Magic mushroom compound tested for cocaine addiction safety

NCT ID NCT06102434

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether a single 25 mg dose of psilocybin (the active ingredient in magic mushrooms) can be safely given to people with cocaine use disorder who want to quit. Ten adults from Los Angeles will take the drug in a comfortable room with two clinicians present, and their heart rate, blood pressure, and mood will be checked for six hours. Researchers will also follow up remotely for 90 days to monitor any lasting effects. The goal is to see if psilocybin is safe enough to study further as a treatment for cocaine addiction.

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Conditions

The condition(s) this trial relates to.

cocaine dependence

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States