Magic mushroom compound tested for cocaine addiction safety

NCT ID NCT06102434

First seen Nov 01, 2025 · Last updated May 16, 2026 · Updated 32 times

Summary

This study looks at whether a single 25 mg dose of psilocybin (the active ingredient in magic mushrooms) can be given safely to people with cocaine use disorder who want to quit. Ten adults from Los Angeles will take the drug in a comfortable room with two clinicians present, and their heart rate, blood pressure, and mood will be checked every hour for six hours. Researchers will also follow up remotely for 90 days to see how they are doing.

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Contacts and locations

Locations

  • University of California, Los Angeles

    Los Angeles, California, 90095, United States

Conditions

Explore the condition pages connected to this study.