University Of California, Los Angeles

This study is testing if a drug called brivaracetam, normally used for epilepsy, can help people with early Alzheimer's disease or mild memory problems. Researchers suspect some memory loss might be linked to hidden seizure-like activity in the brain. Participants will have brain…

This study is testing if drinking watermelon juice daily can improve markers of heart and metabolic health, like blood pressure and cholesterol, and boost the body's natural defenses against stress. Researchers will measure effects right after drinking and again after four weeks …

This study is testing if sodium bicarbonate (a common, low-cost substance) can work as well as the standard, more expensive prescription medication (potassium citrate) to help prevent kidney stones. Researchers will compare how well each treatment makes a person's urine less acid…

This study aims to see if trained peer guides can help people living with HIV who also use substances stay connected to their medical care in Los Angeles. Researchers will work with 250 participants to test whether having a supportive person who understands their experiences help…

This study is testing whether giving sodium lactate through an IV can help the brain heal after a severe traumatic injury. It will involve 264 patients in intensive care units across 10 medical centers. The research aims to find the safest, most effective dose and see if this tre…

This study is testing a new, specially designed food to treat severe malnutrition in children aged 6 months to 5 years. Researchers want to see if this new food helps children recover physically and also improves their brain development and thinking skills. They will compare the …

This study is testing whether a special, easy-to-absorb form of curcumin—the active ingredient in turmeric—can help slow down age-related memory decline. Researchers will enroll 240 adults aged 50-85 who have noticed their memory slipping but do not have dementia. Participants wi…

This study is testing a new way to deliver a long-acting HIV prevention injection called lenacapavir. It will be offered from mobile health vans to 100 people in Los Angeles County who are experiencing homelessness or unstable housing. The main goals are to see how many people st…

This study is testing whether a minimally invasive procedure can prevent dangerous stomach vein bleeding in people with liver cirrhosis. Researchers will compare the procedure, which blocks off the swollen veins, against the current standard of medication alone. The goal is to se…

This study is testing whether a non-invasive brain stimulation technique using magnets can help reduce symptoms of anorexia nervosa. It will involve 45 young people aged 14-24 who will receive 20 daily treatment sessions over 4 weeks. Researchers will track changes in eating diso…

This study tests whether a new FDA-approved non-opioid pain medication called Suzetrigine can reduce patients' need for opioid painkillers after common outpatient knee surgeries. Researchers will compare pain control and side effects between patients receiving the new drug versus…

This study is testing a new, personalized online tool designed to help older adults better understand their lab results for chronic kidney disease. Researchers will ask about 255 patients and their doctors to try different versions of the tool and share their feedback. The goal i…

UCLA researchers are testing a new tool designed to help older adults better understand their lab results. The tool personalizes information based on individual health data and calculates personal risk levels. The study will measure whether this approach reduces anxiety compared …

This study aims to understand how inflammation in the body affects mood and alcohol cravings in people with alcohol use disorder (AUD). Researchers will give 64 participants (half with AUD, half without) a single, low-dose IV infusion that triggers a temporary inflammatory respon…

This early-stage study aims to understand how oral THC and CBD pills affect people's thinking, mood, and how long they can be detected in saliva. Researchers will give these compounds to 22 healthy adults who occasionally use cannabis and measure their performance on thinking tas…

This study is testing a portable, non-invasive brain scanner to see if it can detect brain activity in patients with severe consciousness disorders, like coma. Researchers will first test the scanner on healthy adults, then use it on patients in the intensive care unit to see if …