Can a pill mimic cannabis? new study tests oral THC and CBD

NCT ID NCT05067387

Not yet recruiting Knowledge-focused Sponsor: University of California, Los Angeles Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will give 22 occasional cannabis users oral THC, CBD, both, or a placebo to measure how these substances appear in blood and saliva, and how they affect thinking and behavior. The goal is to better understand drug detection and impairment from oral cannabinoids. It is an early-phase trial that does not aim to treat any disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: THC and CBD (cannabinoids)
What this could lead to: If successful, this could improve understanding of how oral cannabinoids affect driving impairment and drug testing.
What could go wrong: This is a very small, early-phase study (22 people) in occasional users only, so results may not apply to heavy users or real-world settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

poisoning substance abuse substance-related disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRUG ABUSE IMPAIRMENT INTOXICATION BY DRUG

Contacts and locations

Locations

University of California, Los Angeles

Los Angeles, California, 90095, United States

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Other studies related to the condition(s) this trial covers.