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Whipped cream or car cabin? study tracks nitrous oxide in blood, breath, and urine

NCT ID NCT07690358

Knowledge-focused Sponsor: University of Aarhus Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This study measures how long nitrous oxide can be detected in blood, exhaled air, and urine after three types of exposure: inhaling cartridges in a car, eating whipped cream, or working as a midwife in a delivery room. Researchers will track levels for up to two hours. The goal is to understand how different exposures affect detection times, which could inform safety and legal guidelines.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Nitrous Oxide
What this could lead to
If successful, this study could help improve safety guidelines for nitrous oxide exposure in recreational and occupational settings.
What could go wrong
This is a small observational study with only 40 participants, so results may not apply to everyone. It measures detection times, not health effects or risks.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jun 2026

Expected to finish

Dec 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

For arm 1, 2, and 3: Inclusion Criteria: * Age 18-65 years * Able to understand Danish * Willing to use effective contraception for 24 hours after the end of exposure (oral contraceptives, contraceptive implant, transdermal patch, vaginal ring, or injectable contraceptives) * Written informed consent Exclusion Criteria: * Current or past abuse of drugs, nitrous oxide (N₂O), or alcohol * A psychiatric disorder requiring medical treatment, including severe depression * A diagnosis of epilepsy * Symptoms of peripheral neuropathy * Significant cardiac or pulmonary disease * Previous allergic or adverse reaction to N₂O * Diving within the past 2 days * Inability to refrain from diving for 2 days after the study * Occupational exposure to N₂O * Use of N₂O within the past 3 months * Treatment with methotrexate, benzodiazepines, opioids, or other centrally depressant drugs * Recent intraocular gas injection * Known impaired liver or kidney function * Pregnant or breastfeeding women (fertile women, defined as amenorrhea for less than 12 months, must have a negative hCG pregnancy test prior to receiving the study intervention)

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Conditions

The condition(s) this trial relates to.

Driving Under the Influence poisoning

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Intoxication by drug

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Forensic Medicine

    RECRUITING

    Aarhus, 8200, Denmark

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