Diabetes drug shows promise for weight loss in Large-Waisted adults

NCT ID NCT05949008

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether the diabetes drug metformin, combined with a low-calorie diet, helps overweight or obese adults with a large waistline lose weight. About 150 participants will take either metformin or a placebo for 24 weeks. The main goal is to see if at least 5% of body weight is lost, and how the treatment affects quality of life and physical activity.

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Conditions

The condition(s) this trial relates to.

Obesity obesity disorder type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • UCLA Center for Human Nutrition

    Los Angeles, California, 90024, United States