Tailored brain zaps could revolutionize depression treatment

NCT ID NCT06572683

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study explores a personalized form of brain stimulation called resonant frequency rTMS for people with major depression. Researchers will test different stimulation frequencies to see which one best engages brain circuits. The goal is to develop a more targeted treatment approach. The study involves 84 participants and uses brain imaging and EEG to measure effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Transcranial Magnetic Stimulation (TMS)
What this could lead to
If successful, this could lead to more effective, personalized brain stimulation treatments for depression.
What could go wrong
This is an early-stage study focused on measuring brain activity, not on treating depression directly. It may not lead to better outcomes for patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of California

    Los Angeles, California, 90024, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.