MDD
Clinical trials for MDD explained in plain language.
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Brain-Zapping mushroom therapy tested for deep depression
Disease control Recruiting nowThis study is testing whether combining psilocybin (a psychedelic compound) therapy with a rapid form of non-invasive brain stimulation is safe and more effective for treating severe depression that hasn't responded to other treatments. One hundred adults will receive either a hi…
Matched conditions: MDD
Phase: PHASE2 • Sponsor: University of Texas at Austin • Aim: Disease control
Last updated Apr 01, 2026 14:42 UTC
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Home Brain-Zap kit tested to lock in depression recovery
Disease control Recruiting nowThis small pilot study is testing whether people who have recently gotten better from severe depression can use a simple, portable brain stimulation device at home to help keep their symptoms from coming back. Participants who improved after hospital treatment will use the device…
Matched conditions: MDD
Phase: NA • Sponsor: Technical University of Munich • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Can a fish oil pill ease depression?
Symptom relief Recruiting nowThis study is testing whether taking a high dose of a specific fish oil (EPA) for 12 weeks can help reduce depression symptoms in overweight or obese adults who also have low levels of omega-3 in their blood. Researchers will compare the fish oil against a placebo (dummy pill) in…
Matched conditions: MDD
Phase: NA • Sponsor: National Science and Technology Council, Taiwan • Aim: Symptom relief
Last updated Mar 18, 2026 14:41 UTC
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Scientists map brain to predict depression treatment success
Knowledge-focused Recruiting nowThis study aims to understand how brain networks change during TMS (transcranial magnetic stimulation) therapy for depression. Researchers will observe 100 patients already receiving standard TMS treatment to see if brain scans can predict who responds best. The goal is to learn …
Matched conditions: MDD
Sponsor: Goethe University • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC