Can fish oil lift depression in obese adults?

NCT ID NCT07439744

Recruiting now Symptom relief Sponsor: National Science and Technology Council, Taiwan Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether taking omega-3 (EPA) supplements for 12 weeks can reduce depressive symptoms in overweight or obese adults who have depression and low omega-3 levels. Half of the 50 participants will receive EPA, and half will receive a placebo. Researchers will also look at how inflammation, diet, and gut bacteria relate to mood changes.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Eicosapentaenoic acid (EPA), an omega-3 fatty acid
What this could lead to: If it works, this could point toward a simple dietary supplement option for reducing depression in overweight people with low omega-3 levels.
What could go wrong: This is a small, early-stage trial with only 50 participants. The effect may be modest or no better than placebo, and results may not apply to everyone with depression.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for MAJOR DEPRESSIVE DISORDER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

endogenous depression major depressive disorder obesity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MDD OBESE ADULTS

Contacts and locations

Locations

Mind Body Interface Research Center (MBI Lab & Care)
RECRUITING

Taichung, Taichung, 404, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.