MDD
Clinical trials for MDD explained in plain language.
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Tailored magnetic pulses aim to restore pleasure in depressed patients
Symptom relief CompletedThis study tested a personalized form of brain stimulation for people with depression who no longer feel pleasure (anhedonia). Sixty adults received either individualized, standard, or fake magnetic pulses to the brain over one week. The goal was to see if tailoring the stimulati…
Matched conditions: MDD
Phase: NA • Sponsor: University of California, San Diego • Aim: Symptom relief
Last updated Jun 27, 2026 09:05 UTC
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Can VR fun beat the blues? small trial tests virtual activities for depression
Symptom relief CompletedThis study tested whether using a virtual reality (VR) headset to do fun activities could help ease depression symptoms. 26 adults with major depression were asked to complete at least four activities each week, either in VR or in real life. Researchers measured changes in depres…
Matched conditions: MDD
Phase: NA • Sponsor: Stanford University • Aim: Symptom relief
Last updated Jun 27, 2026 07:51 UTC
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Brain scans train depressed minds to look away from negativity
Symptom relief CompletedThis study tested whether real-time brain scans (fMRI) could help people with major depression learn to stop focusing on negative thoughts. 71 adults received either active or sham neurofeedback while doing a task. The goal was to see if changing brain patterns could reduce depre…
Matched conditions: MDD
Phase: NA • Sponsor: University of Pennsylvania • Aim: Symptom relief
Last updated Jun 26, 2026 14:46 UTC
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Generic depression patch tested against brand in small study
Knowledge-focused CompletedThis study tested whether a generic selegiline skin patch works the same as the brand-name EMSAM patch. Twelve healthy adults wore both patches to measure how much drug got into their blood and to check for skin irritation. The goal was to see if the generic version is a safe and…
Matched conditions: MDD
Sponsor: Corium Innovations, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC