MDD
Clinical trials for MDD explained in plain language.
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Online depression program for orthopedic patients pulled before starting
Symptom relief TerminatedThis study aimed to see if a web-based self-help program called Deprexis could help orthopedic patients with major depressive disorder. The plan was to offer the 8-week online program to patients with depression and see if they would use it and if their mood and physical function…
Matched conditions: MDD
Phase: NA • Sponsor: Jasper A. Smits • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Could a facial zapping device treat depression at home?
Symptom relief OngoingThis study tests whether a device that sends mild electrical pulses to facial muscles can help treat major depression. Twenty adults with depression will use the device at home for 45 minutes daily over four weeks. The main goal is to see if the approach is feasible and safe, wit…
Matched conditions: MDD
Phase: NA • Sponsor: Unity Health Toronto • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Could magnetic pulses lift depression in autism?
Symptom relief OngoingThis study tests whether a type of brain stimulation called rTMS can reduce depression in people with autism. Twenty-four participants aged 13 to 26 will receive either real or sham (fake) stimulation to see if it helps. The goal is to find a new way to treat depression that hasn…
Matched conditions: MDD
Phase: NA • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Symptom relief
Last updated Jun 27, 2026 09:04 UTC
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Tailored brain zaps could revolutionize depression treatment
Knowledge-focused ENROLLING_BY_INVITATIONThis study explores a personalized form of brain stimulation called resonant frequency rTMS for people with major depression. Researchers will test different stimulation frequencies to see which one best engages brain circuits. The goal is to develop a more targeted treatment app…
Matched conditions: MDD
Phase: NA • Sponsor: University of California, Los Angeles • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC