Brain scans may predict who benefits from TMS for depression

NCT ID NCT07422844

Recruiting now Knowledge-focused Sponsor: Goethe University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study observes 100 people with depression who are already receiving transcranial magnetic stimulation (TMS) therapy. Researchers use brain scans and symptom questionnaires to see how brain networks change during treatment and whether these changes can predict who gets better. The goal is to understand why TMS works for some people but not others.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If successful, this could help doctors predict which depression patients will benefit from TMS therapy, making treatment more personalized.
What could go wrong: This is an observational study, not a treatment trial. It aims to understand brain changes, not to prove TMS works. Results may not lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

endogenous depression major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MDD

Contacts and locations

Locations

Klinik für Psychiatrie, Psychosomatik und Psychotherapie
RECRUITING

Frankfurt am Main, Hesse, 60528, Germany

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