Can psychedelics and brain zaps beat stubborn depression?

NCT ID NCT06132178

First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 34 times

Summary

This study is for adults aged 22-65 with major depression that hasn't improved with standard treatments. Researchers want to see if giving psilocybin (the active ingredient in magic mushrooms) followed by a type of brain stimulation called aiTBS is safe and can help lift depression. The study will involve 100 participants and use brain scans and questionnaires to measure changes in mood and brain activity.

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Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Health Discovery Building (HDB), 1601 Trinity St., Bldg B., Z0600

    RECRUITING

    Austin, Texas, 78712, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.