Brain scans and stress tests aim to unravel PMDD vs depression
NCT ID NCT06130371
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares women with PMDD, major depressive disorder (MDD), and healthy controls to see how their brains, stress responses, and inflammation differ. Researchers will use brain scans, stress tasks, and blood/saliva tests in 75 naturally cycling women aged 18-40. The goal is to better understand PMDD and distinguish it from MDD.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could improve understanding of PMDD and its differences from MDD, potentially guiding better diagnosis or future treatments.
- What could go wrong
- This is an observational study with only 75 participants, so results may not apply to everyone. It aims to gather knowledge, not test a treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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University Hospital Tübingen, Klinik für Psychiatrie und Psychotherapie
RECRUITINGTübingen, Baden-Wurttemberg, 72076, Germany
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