Beth Israel Deaconess Medical Center

This study tested whether adding an experimental antibody (CT-011) and a personalized cancer vaccine to standard stem cell transplant is safe and helps prevent multiple myeloma from coming back. 35 adults with multiple myeloma received the combination after transplant. The goal w…

This early-phase trial tested a personalized vaccine for people with advanced kidney cancer. The vaccine was made by fusing a patient's own immune cells with their tumor cells, aiming to train the body to attack the cancer. The main goals were to check safety and see if the vacci…

This study tested a new blood test that measures how well platelets work in people taking common anti-clotting drugs like aspirin and clopidogrel. Researchers compared this new test to the current standard test in 112 healthy volunteers and severely obese individuals. The goal wa…

This study tested whether giving older adults (60+) a common painkiller (acetaminophen) through an IV every 6 hours during heart surgery could prevent postoperative delirium—a state of sudden confusion that often occurs after major operations. Researchers enrolled 900 patients un…

This study tested whether a non-invasive brain stimulation technique (transcranial electrical stimulation) could reduce mania symptoms in people with bipolar or schizoaffective disorder. Fourteen adults with mild to moderate mania received the stimulation targeting a brain area l…

This small study tested whether a noninvasive electrical stimulation technique, aimed at a specific brain area called the right superior temporal sulcus, could help reduce hallucinations in people with psychosis. Twelve adults who were actively experiencing hallucinations receive…

This study tested a brief cognitive behavioral therapy (CBT) program to help older adults (55 and older) reduce or stop taking benzodiazepines, which are often used for anxiety or sleep problems. Seventeen participants received the therapy and were followed to see if they could l…

This small pilot study looked at whether a 12-week tai chi program is practical and beneficial for people with chronic obstructive pulmonary disease (COPD). Ten adults with COPD were randomly assigned to either tai chi or their usual care. The study focused on whether tai chi cou…

This study tested a special anesthesia method during heart surgery to help older adults recover better. The goal was to reduce confusion, pain, and blood pressure problems after surgery. 70 people aged 60 and older who had heart bypass or valve surgery took part. The approach use…

This study tested a daily synbiotic (a mix of probiotics and prebiotics) called DS-01 in 48 adults with irritable bowel syndrome (IBS). The goal was to see if it is safe and helps improve gut barrier function and digestive symptoms compared to a placebo. Participants took the sup…

This study looked at whether using ultrasound to guide epidural needle placement works better than the usual method of feeling for landmarks (palpation) in women experiencing labor pain. Researchers compared how often the catheter was placed at the right spot and how long the pro…

This study looked at whether giving low-dose nitrous oxide (laughing gas) during a urodynamic study (a test for urinary symptoms) changes the test results. 19 adults scheduled for the test took part. The goal was to see if the gas could reduce pain and anxiety without affecting i…

This study tested whether a walking program, a mindfulness program, or a combination of both could help people with metabolic syndrome become more active. Thirty-four participants were assigned to one of four groups: walking only, mindfulness only, walking plus mindfulness, or no…

This study looked at whether long-term meditation practice is linked to a younger-looking brain and better sleep. About 108 adults (57 meditators and 51 non-meditators) wore sleep-tracking devices for five nights and took cognitive tests. Researchers compared brain age estimates …

This study tested whether a conversational AI system can safely and effectively take a patient's medical history before an urgent care visit. About 100 adults spoke with the AI, supervised by a doctor, and researchers measured safety, patient satisfaction, and the quality of the …

This pilot study tested whether a multi-component prehabilitation program (physical therapy, nutrition counseling, and meditation) is feasible for high-risk older adults scheduled for major elective surgery. Thirty participants aged 70+ (or 65+ with high risk) were enrolled. The …