Electric brain zap tames mania in small trial

NCT ID NCT05445466

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a non-invasive brain stimulation technique to reduce mania symptoms in people with bipolar or schizoaffective disorder. Fourteen participants with mild-to-moderate mania received targeted electrical stimulation to brain areas linked to impulse control and risk-taking. The goal was to see if this approach could safely lower manic symptoms without the side effects of standard medications.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Beth Israel Deaconess Medical Center

    Boston, Massachusetts, 02215, United States

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