Zapping the brain to calm mania: small study shows promise
NCT ID NCT05445466
First seen Nov 06, 2025 · Last updated Apr 29, 2026 · Updated 19 times
Summary
This study tested whether a non-invasive brain stimulation technique (transcranial electrical stimulation) could reduce mania symptoms in people with bipolar or schizoaffective disorder. Fourteen adults with mild to moderate mania received the stimulation targeting a brain area linked to impulse control and risk-taking. The goal was to see if this approach could safely ease manic episodes without the side effects of current medications.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Locations
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Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
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