Which drug works best for Post-C-Section nausea? study pits dexamethasone against ondansetron
NCT ID NCT05692245
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 100 healthy women having a planned or non-labor cesarean delivery to see which drug works better as a first-line treatment to prevent nausea and vomiting after surgery. Participants received either dexamethasone or ondansetron, and researchers tracked how many extra medications they needed for nausea, vomiting, itching, or pain in the first 24 hours. The goal is to find the most effective option to improve comfort after C-section.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- dexamethasone and ondansetron
- What this could lead to
- If successful, this could help doctors choose the best first-line antiemetic for women after cesarean delivery, improving recovery comfort.
- What could go wrong
- This is a small, completed Phase 4 trial with only 100 participants, so results may not apply to all patients. Both drugs are well-known, so no major surprises are expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Beth Israel Deaconess Medical Center
Boston, Massachusetts, 02215, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- When pain strikes during C-Section: what Women's stories reveal
- Which drug stops Post-Birth bleeding better? a Head-to-Head test
- Cheaper, Needle-Free option for Post-Surgery nausea in children put to the test
- Mind over matter: pain catastrophizing may predict Post-Surgery nausea
- Simple C-Section techniques could slash postpartum bleeding risk