Beth Israel Deaconess Medical Center

Sepsis harms the protective lining of blood vessels, leading to organ failure. This study tests whether giving fresh frozen plasma—either as short bursts or a steady drip—can repair that lining better than a placebo. About 45 ICU patients with sepsis will be enrolled, and researc…

This study tests a new way to care for people with pacemakers or defibrillators. Instead of routine checkups, doctors will only see patients when the device sends a specific alert. The goal is to see if this alert-driven approach is safer and more effective than standard care. Ab…

This pilot study will test whether an iPad app called DCog Short can spot early signs of brain-related side effects (neurotoxicity) in people receiving CAR-T cell therapy for blood cancers. About 40 participants will use the app to self-report symptoms, and researchers will compa…

This study looks at whether adding a short daily guided meditation practice to mindfulness education can improve how engaged and well employees feel at work. About 134 adult workers will use a smartphone app and complete surveys over 12 weeks. The goal is to see if the combined a…

This study tests whether a numbing gel (topical lidocaine) can reduce pain when placing a cervical ripening balloon, a common step to start labor. About 110 pregnant women at full term will be randomly assigned to receive the gel or a placebo. The goal is to see if the gel makes …

This study looks at whether simple breathing exercises and guided meditations can improve mental health for elderly ICU survivors (over 60) and their caregivers. Participants will practice these techniques using a mobile app or in a group, and complete surveys about their mood an…

This study tests whether a short, daily meditation app can help young adults feel better, less stressed, and more resilient. About 354 people aged 18-40 in the US will be randomly assigned to do a 7-minute meditation, listen to a neutral audio, or continue their normal routine fo…

This study looks at how changing the pressure on a breathing machine (called PEEP) affects the heart's pumping ability in adults during heart surgery. Researchers will monitor 28 participants using ultrasound and other tools to measure heart function at different pressure levels.…

This study looks at whether a meditation program called Inner Engineering can help teens ages 15-18 become more joyful, focused, and resilient. Researchers will measure changes in emotional wellbeing, stress, and even brain activity using surveys, body sensors, and brain scans. T…

This study looks at whether giving high-flow oxygen through the nose during and after robotic surgery can prevent dangerous drops in oxygen levels and lung problems. About 190 adults having robotic surgery will take part. The goal is to see if this approach improves safety during…

This study tests a special microscope that lets surgeons check for leftover cancer cells right after removing the prostate. About 20 men with prostate cancer will have their removed tissue scanned during surgery. The goal is to see if this method works well and can help surgeons …