Sohag University

This study looks at whether a modified Atkins diet can help children aged 1 to 18 with drug-resistant epilepsy. Researchers will track seizure control, quality of life, thinking skills, and growth. The goal is to see if this diet offers a safe, effective way to manage seizures wh…

This study looks at two surgical ways to fix bow legs or knock-knees in children who are still growing. About 60 kids aged 3 and up will get either screws or plates to help straighten the leg. The goal is to see which method works better and faster, and to reduce the risk of knee…

This study tests whether SGLT2 inhibitors, a type of diabetes medicine, can improve anemia in people with chronic kidney disease (CKD). Anemia is common in CKD and often requires iron or other injections, which have side effects. The trial will measure changes in hemoglobin level…

This study compares two surgical techniques for repairing a torn ligament in the finger (volar plate injury). The standard method uses a suture that passes through the skin, which can cause irritation and delay movement. The newer method uses a small internal anchor, which may al…

This study compares two treatments for stable vitiligo, a condition that causes white patches on the skin. One group gets microneedling with a minoxidil solution, while the other gets the same plus narrow-band UVB light therapy. The goal is to see which approach better restores s…

This study tests two different laser settings (5% vs 15% duty cycle) to treat diabetic macular edema, a condition where fluid builds up in the eye's center. About 50 adults with mild to moderate vision loss will receive one of the two laser treatments. The goal is to see which se…

This study tests a surgical technique to correct a rare condition where the two bones in the forearm are fused together, limiting rotation. The surgery involves cutting and repositioning the bones, then holding them in place with temporary wires. The goal is to improve arm functi…

This early-stage study tests whether a daily saline-glycerin enema can help children with fecal incontinence (leaking stool) stay clean. About 30 children aged 3 to 16 with conditions like corrected anorectal malformation or Hirschsprung disease will use the enema once a day. The…

This study tests whether a combination of three medicines—glucose-insulin-potassium infusion, hydrocortisone, and sevelamer—can lower the death rate in people who have been poisoned by aluminum phosphide, a common pesticide used to protect stored grains. The trial will enroll 74 …

This study compares two injection treatments for common warts: platelet-rich fibrin (a natural substance from your own blood) and vitamin D. About 70 adults with warts will receive one of these injections to see which works better and is safer. The goal is to shrink or clear the …

This study will enroll 30 men with stable male pattern baldness to compare two add-on treatments—platelet-rich plasma (PRP) and nanofat—given alongside standard hair transplantation. The goal is to see which method better improves graft survival, hair density, and thickness, as w…

This study looks at whether measuring two substances in the blood—IL-6 and MMP-7—can help doctors diagnose and predict the course of a rare lung condition in children called immune-mediated interstitial lung disease. Researchers will compare levels in 60 children with the disease…

This study will check how accurate MRI and ultrasound are at identifying superficial soft tissue masses (lumps under the skin). About 50 people with these lumps will be scanned, and the results will be compared to the final diagnosis. The goal is to see if these imaging tests can…

This study will check how accurate MRI is at finding and describing perianal fistulas (abnormal tunnels near the anus) and related problems like abscesses. About 30 people who need surgery for a suspected fistula will get an MRI first. Doctors will then compare the MRI results wi…

This study looks at whether a non-invasive stool test (qFIT) can accurately detect colorectal cancer and precancerous lesions in adults aged 40–75. Researchers will compare the test results with colonoscopy findings to see how well it works for different types and locations of gr…

This study will check how well MRI can tell if ovarian cysts are harmless or cancerous. About 50 women with cysts seen on ultrasound will get an MRI. Results will be compared with surgery findings or follow-up scans to see if MRI improves diagnosis and helps doctors choose the ri…

This study looks at whether a simple blood test called the Systemic Immune Inflammation Index (SII) can help doctors diagnose and predict acute kidney injury (AKI) in people with liver cirrhosis. AKI is a common and serious complication in cirrhosis, but current tests are often u…

This study will test whether a type of MRI called diffusion-weighted imaging can accurately tell the difference between non-cancerous and cancerous growths in the lining of the uterus. About 30 women with abnormal bleeding or suspicious ultrasound findings will receive the MRI, a…

This study will check if a specific ultrasound finding called the 'rail sign' can accurately detect placenta accreta in pregnant women who have placenta previa. About 90 women in their second or third trimester will be scanned. The goal is to see if this sign helps doctors diagno…

This study looks at whether a hormone called irisin can be used to detect diabetic kidney disease early and track its progression. Researchers will measure irisin levels in 200 people with type 2 diabetes and compare them to healthy individuals. The goal is to find a simple blood…

This study compares two types of nerve blocks to see which provides better pain relief after open gallbladder removal. Sixty-six adults having this surgery will receive one of the two blocks along with standard anesthesia. The goal is to find which method reduces pain and the nee…

This study compares two anesthesia methods for strabismus (eye muscle) surgery in adults: general anesthesia (being fully asleep) versus a combination of sedation with a local anesthetic injection around the eye. The goal is to see which method leads to higher patient and surgeon…

This study compares two types of pulsed radiofrequency treatments for people with long-lasting nerve pain after shingles (postherpetic neuralgia). One hundred adults whose pain has not responded to standard treatments will receive either a standard or a new irregular pulsed radio…

This study compares two surgical methods for fixing a broken ankle bone (lateral malleolus). About 52 adults with specific ankle fractures will receive either a plate and screws or a single screw placed inside the bone. The goal is to see which approach leads to faster healing, b…

This study looks at common nose structure problems in people getting nose surgery (septorhinoplasty) and tests ways to fix them. About 25 people aged 16 to 60 will take part. The goal is to improve both how the nose looks and how well it works for breathing.

This study tests if a newer type of pulsed radiofrequency (called STP) is safer and works better than the standard type for treating severe facial pain from trigeminal neuralgia. About 62 adults whose pain is not controlled by medication will receive one of the two procedures. Re…

This study compares two additives (midazolam and cisatracurium) mixed with lidocaine to see which one makes eye muscles go numb faster during retinal surgery. 90 adults having elective retinal surgery will be randomly assigned to one of three groups. The goal is to find the safes…

This study compares two treatments for people with chronic migraine who haven't found relief from standard medicines. One treatment is a nerve block injection, and the other is a procedure called pulsed radiofrequency. The goal is to see which one reduces pain better and improves…

This study compares two types of nerve blocks (retrolaminar block and erector spinae plane block) for pain relief after laparoscopic gallbladder removal. One hundred adults aged 20-60 will be randomly assigned to receive one of the two blocks. The main goal is to see which block …

This study tests whether adding salt water (sodium chloride 5%) eye drops to standard antibiotic treatment helps heal bacterial eye infections faster. Researchers will check if the salt water speeds up healing of the cornea, kills bacteria better, and improves eyesight. The study…

This study compares two minimally invasive treatments for carpal tunnel syndrome: pulsed radiofrequency and hyaluronidase hydrodissection. Researchers will measure pain relief, hand function, and nerve health in 56 adults aged 20-80 with mild to moderate symptoms. The goal is to …

This study tests whether breathing in ketamine or magnesium sulfate before surgery can prevent or lessen sore throat after general anesthesia. 150 adults having elective surgery with a breathing tube will be randomly assigned to one of the two treatments. The goal is to find a be…

This study tests a newer, less invasive surgical technique for otosclerosis, a condition that causes hearing loss by hardening a tiny bone in the ear. Researchers will use a small camera (endoscope) instead of a microscope to perform the surgery. The goal is to see if this approa…

This study compares three medications—magnesium sulphate, ondansetron, and dexmedetomidine—to see which works best for stopping shivering after spinal anesthesia. Sixty adults having lower abdominal or leg surgery will take part. The main goal is how quickly shivering stops, and …

This study will compare two types of nerve blocks—ESP block and TAP block—to see which provides better pain relief after a cesarean section. Sixty women having a planned C-section will be randomly assigned to receive one of the two blocks. The goal is to measure pain levels, how …

This study compares two minimally invasive surgical techniques (uniportal vs. biportal endoscopy) for treating a single-level herniated lumbar disc. Sixty adults aged 18-70 who have not improved with at least 6 weeks of non-surgical care will be enrolled. The main goal is to meas…

This study tests whether microneedling (tiny needles that prick the skin) combined with either tretinoin or timolol cream can improve the look of early red stretch marks. About 300 adults with these marks will receive the treatment, and doctors will track changes through photos a…

This study compares two common anesthesia drugs—propofol and sevoflurane—during a type of eye surgery called cyclophotocoagulation. The goal is to see which one keeps eye pressure more stable and causes fewer heart-related side effects. Forty adults with cataracts will take part,…

This study will compare two groups of people with psychosis: those whose symptoms are caused by methamphetamine use and those with schizophrenia. Researchers will track 200 adults in Sohag, Egypt, using interviews and symptom scales to see how the two conditions differ in severit…

This study will observe 200 adults with intermediate-stage liver cancer to see which treatments doctors actually use and how long patients survive. Researchers will not give any new treatment—they will just collect data from medical records. The goal is to understand current care…

This study will check if different types of anemia (like iron deficiency or thalassemia) cause HbA1c blood sugar tests to be falsely high or low in adults without diabetes. About 100 non-diabetic adults with anemia will be compared to a healthy group. The goal is to help doctors …

This study looks at whether a simple calculation using heart rate and blood pressure (called the Modified Shock Index) can help predict how serious sepsis will be for patients in the emergency room. Researchers will follow 70 adults with sepsis to see if this measure relates to o…

This study will collect urine, pus, and sputum samples from 100 hospital patients with multidrug-resistant Klebsiella pneumoniae infections. Researchers will test the bacteria for their ability to form biofilms (protective slime layers) and pump out antibiotics. They will also lo…

This study is checking if omega-6 fatty acids in the blood are connected to liver cancer. Researchers will compare levels in 100 adults with liver cancer to those in healthy people. The goal is to see if these fats might be linked to the disease, not to test a treatment.

This study will observe 50 children (ages 1 month to 18 years) who come to the emergency room at Sohag University Hospitals with kidney-related symptoms like swelling, blood in urine, or high blood pressure. Researchers want to learn which kidney problems are most common and how …

This study will follow 100 newly diagnosed breast cancer patients in Egypt to see how chemotherapy affects their thinking, memory, and emotions. Researchers will use questionnaires and tests before treatment and one year later. The goal is to better understand these side effects …

This study looks at how changes in blood sugar levels affect the health of diabetic patients with heart disease who are in the coronary care unit. Researchers will track 120 adults to see if large blood sugar swings lead to more deaths or serious heart problems like heart attacks…

This study looks at 400 people with lupus to compare those with typical symptoms (like joint pain and rash) to those with unusual or late-onset symptoms. The goal is to see if atypical cases lead to worse outcomes, more organ damage, or different treatment needs. By understanding…

This study aims to understand how dry eye disease and diabetic macular edema (a cause of vision loss) are related in people with diabetes. About 50 adults aged 18-60 with diabetes for over 8 years will undergo eye exams and questionnaires. The goal is to improve knowledge, not to…

This study will survey 402 female medical students at Sohag University to understand how painful periods (primary dysmenorrhea) affect their school performance and quality of life. Participants will fill out two questionnaires about their pain and its impact. The goal is to gathe…

This study looks at how many people on long-term hemodialysis experience anxiety or depression. Researchers will survey 160 patients at Sohag University Hospital to find out how common these issues are and what factors might be linked to them. The goal is to better understand the…

This study looks at two genes, IL-1β and IL-33, in 300 adults with either primary immune thrombocytopenia (ITP) or lupus-related low platelets. The goal is to see if these genes can help doctors tell the two conditions apart more easily. Participants will give a blood sample, and…

This study looks at 50 adults with acute pulmonary embolism (a blood clot in the lungs) to compare how well different tests—like clinical scoring, blood markers, and CT scans—work in various hospital departments. The goal is to find the most reliable tools for early diagnosis and…

This study will test 250 people with tuberculosis (TB) to see how many have drug-resistant strains. Using special tests called GeneXpert, researchers will identify resistance to key drugs like Rifampicin. They will also look for risk factors such as diabetes or drug addiction tha…

This study looks at how different types of anesthesia affect the success and safety of a procedure called ERCP, used to treat obstructive jaundice. Researchers will track 100 adults to see which anesthesia leads to better results, fewer complications, and higher satisfaction for …

This study looks at whether certain fat molecules (ceramides and sphingosine-1-phosphate) in the blood are different in people with acne compared to healthy people. Researchers will collect blood samples from 80 participants (40 with acne and 40 without) to measure these molecule…

This study will compare the quality of life of 50 children aged 6 to 18 who have a primary immunodeficiency (a weak immune system from birth) with healthy children of the same age. Researchers will use a simple questionnaire to measure physical, emotional, social, and school func…

This study looks at 100 people with rectal cancer who received total neoadjuvant therapy (a combination of chemotherapy and radiation before surgery). Researchers want to see whether the status of lymph nodes after treatment or the shrinkage of the main tumor better predicts how …

This study will use a special eye scan called OCTA to look for early signs of retinal damage in 90 adults who have taken hydroxychloroquine for at least a year. Hydroxychloroquine is a common medication for autoimmune diseases, but long-term use can harm the retina. The goal is t…

This study will follow 100 adults hospitalized for a sudden worsening of bronchiectasis. Researchers will track how conditions like COPD, diabetes, and heart disease, along with disease severity, affect treatment failure, hospital stay, and survival. The goal is to better predict…

This study will review medical records of 100 adults treated for locally advanced rectal cancer between 2018 and 2025. The goal is to see which treatments were used and how patients fared, including survival and side effects. No new treatments are given—just learning from past ex…

This study looks at how iron buildup from blood transfusions affects the reproductive system in boys aged 10 to 18 with beta thalassemia major. Researchers will measure key hormones to find early signs of problems. The goal is to better understand and detect these issues sooner.

This study looks at how certain genes in a dangerous, drug-resistant bacterium (carbapenem-resistant hypervirulent Klebsiella pneumoniae) affect its response to a powerful antibiotic called cefiderocol. Researchers will collect 100 samples from infected patients and test the bact…

This study will check if three simple blood test ratios (monocyte-to-albumin, neutrophil-to-albumin, and total white blood cell-to-albumin) can predict how severe a stroke is and how well patients recover. Researchers will follow 60 adults with acute ischemic stroke, measuring st…

This study looks at a blood protein called FAP, which is linked to tissue scarring and inflammation. Researchers will measure FAP levels in people with rheumatoid arthritis, systemic sclerosis (scleroderma), and healthy volunteers. The goal is to see if FAP levels relate to disea…

This study aims to find out how common depression is among medical students at Sohag University. About 300 students aged 18 to 25 will be surveyed. The goal is to better understand the mental health challenges faced by medical students, who are under high stress from academics an…

This study looks at whether a routine blood test measuring mean platelet volume (MPV) can help predict acute coronary syndrome (heart attack or unstable angina) in people with metabolic dysfunction-associated steatotic liver disease (MASLD). Researchers will compare MPV levels in…

This study involves 100 university students with type 1 diabetes. Researchers will test their knowledge of carbohydrate counting and then provide a structured education session. After three months, they will check if blood sugar control (HbA1c) and carb counting skills have impro…

This study will observe 40 people in Sohag who have a twisted sigmoid colon, a cause of bowel blockage. Researchers want to show that this condition can affect young people, not just the elderly. The goal is to help doctors diagnose it earlier and avoid serious complications.

This study checks if a formula called fullPIERS can accurately predict which pregnant women with preeclampsia (high blood pressure and protein in urine) will have serious health problems. Researchers will collect medical information from 50 women within 48 hours of admission to s…

This study will compare the biology of the first breast cancer with that of any recurrence in the same patient. Researchers will review medical records of 200 adults treated between 2015 and 2025. The goal is to see how often key markers change, which may guide future treatment d…

This study will follow 300 people with non-spreading bladder cancer who receive high-dose radiation therapy, sometimes with chemotherapy. Researchers will track how long patients live, whether the cancer returns, and any side effects from treatment. The goal is to understand real…

This study compares two types of nerve blocks used during shoulder surgery to see which one is less likely to temporarily paralyze the diaphragm, the main muscle for breathing. Sixty adults having shoulder surgery will be randomly assigned to receive either a standard block or a …

This study looks at whether a blood test measuring the ratio of two substances (IGF-1 and albumin) can help identify muscle loss severity in people with end-stage kidney disease on dialysis. About 110 adults will have their blood tested and compared to standard muscle assessments…

This study aims to find out if people with a common inner-ear dizziness condition called BPPV have lower vitamin D levels than those without it. Researchers will compare vitamin D levels in 160 adults—half with BPPV and half without. The goal is to better understand the possible …

This study aims to see if toxins from gut bacteria are linked to early pancreas problems in lean people with prediabetes. Researchers will measure blood markers of gut toxins and pancreas function in 120 adults aged 18-65 with a healthy weight. The goal is to better understand ho…

This study will check how often heart problems (diastolic dysfunction) occur in 100 adults with kidney failure who are on regular hemodialysis. Researchers will use ultrasound to look at heart function and see how it connects to dialysis factors and other health measures. The goa…

This study will look at 100 people who have a colonoscopy for lower gut symptoms like long-term diarrhea, blood in stool, or belly pain. The goal is to find out which type of colon inflammation they have and what might be causing it. The results could help doctors diagnose and tr…

This study will survey 380 mothers with children up to 24 months old in Sohag, Egypt, to measure how many breastfeed exclusively and what factors influence their choices. Researchers will assess mothers' knowledge and confidence about breastfeeding. The goal is to identify gaps a…

This study aims to see if certain substances in the blood (CCR6 and CCL20) can serve as markers for rheumatoid arthritis. Researchers will compare blood samples from 60 adults with RA to healthy individuals. The goal is to better understand the disease, not to test a new treatmen…

This study looks at hormone levels in 100 children aged 1 to 12 who have dilated cardiomyopathy, a condition where the heart is enlarged and weak. Researchers will take blood samples to measure insulin growth factor and other hormones. The goal is to learn more about how heart fa…

This study aims to find out how common body dysmorphic disorder (BDD) is in children with chronic skin diseases compared to healthy kids. It will include 500 children aged 6 to 18, half with skin conditions and half without. Researchers will use questionnaires to measure BDD symp…

This study looks at how well the antibiotic combination ceftazidime-avibactam works against a hard-to-treat bacteria called Klebsiella pneumoniae that produces carbapenemases (enzymes that break down many antibiotics). Researchers will collect samples from 100 hospitalized patien…

This study will test 200 adults on regular hemodialysis for latent tuberculosis infection (LTBI) using a simple skin test. The goal is to find out how many dialysis patients carry the bacteria without symptoms, so doctors can better prevent active TB in this vulnerable group. No …

This study will look at medical records of 40 children under 18 who came to the hospital with traumatic injuries. Researchers want to find patterns in the types of injuries, how severe they are, and what happens to the children afterward. The goal is to learn more so doctors can …

This study aims to find a specific gene change called Notch1 in the blood or bone marrow of 80 people with either chronic lymphocytic leukemia (CLL) or non-Hodgkin's lymphoma (NHL). Researchers will compare how often the mutation appears in each cancer type. The goal is to better…

This study looks at how local anesthesia given before cataract surgery changes blood flow in the retina, the light-sensitive tissue at the back of the eye. Researchers will use a special imaging technique called OCT angiography to compare blood vessel density before and after the…

This study will look at blood test results from 60 pregnant women with HELLP syndrome, a rare but serious condition. The goal is to see if certain markers in the blood can help predict which women and their babies are at higher risk for severe complications. This is an observatio…

This observational study will measure how often left ventricular hypertrophy (thickening of the heart muscle) occurs in people with chronic kidney disease. It will also test whether erythropoietin, a drug used to treat anemia, can reduce heart muscle thickness in anemic patients.…

This study looks at why some children have persistent low blood sugar (hypoglycemia) that doesn't go away easily. Researchers will check for hormone problems, metabolic disorders, and genetic factors in 50 children from birth to age 18. The goal is to find the root cause so docto…

This study observes 200 pregnant women with placenta accreta (a condition where the placenta grows too deeply into the uterus) to see how often it invades the cervix and whether a short cervix leads to early labor. Researchers will use extra ultrasound scans during routine care—n…

This observational study will follow 200 adults with well-controlled rheumatoid arthritis to find ways to predict when a disease flare might happen. Researchers will track symptoms, disease history, and specific blood markers every 3 months. The goal is to help doctors make bette…

This observational study will measure levels of certain immune proteins (IL-17, IL-38, IL-41) and a gene (HLA-B27) in 84 people with ankylosing spondylitis and healthy volunteers. The goal is to see if these markers are linked to disease activity and severity. No treatment is giv…

This study checks if a set of thinking and drawing tests (called PHES) can find minimal hepatic encephalopathy—a mild form of brain fog—in people with stable liver cirrhosis. About 150 patients and 150 healthy volunteers will take the tests to see how well they detect early cogni…

This study looks at how diabetes and related metabolic problems affect hospitalized patients with chronic kidney disease. Researchers will collect medical information from 200 adults to see if diabetes increases the risk of death, need for dialysis, or serious heart problems duri…

This study aims to find out which method of helping children breathe during anesthesia is best for keeping their eye pressure stable during congenital glaucoma surgery. Researchers will compare three different airway management techniques in 75 children. The goal is to see which …