Could a special diet tame seizures in kids when drugs fail?
NCT ID NCT07275125
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test whether a modified Atkins diet can help children aged 1-18 with drug-resistant epilepsy. Researchers will track seizure control, quality of life, thinking skills, and growth in 40 children who follow the diet for at least 6 months. The goal is to see if this dietary approach offers a safe, non-drug way to reduce seizures and improve daily life.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
This study will include pediatric patients with drug-resistant epilepsy (DRE) attending the ketogenic diet clinic at the Pediatric Neurology Unit, Sohag University Hospital. Eligible participants are children aged 1-18 years who meet the International League Against Epilepsy (ILAE) definition of DRE and have been on a ketogenic dietary therapy, specifically the Modified Atkins Diet (MAD), for at least 6 months.
- Ages
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1 year to 18 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 1-18 years. * Diagnosed with drug-resistant epilepsy according to ILAE definition.\[2\] * On KD for at least 6 months. Exclusion Criteria: * \- Patients with contraindicated metabolic/genetic conditions. * Non-compliance with KD . Patients on alternative dietary therapies (e.g., low glycemic diet)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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Contacts and locations
Locations
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Sohag faculty of medicine
Sohag, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a new implant tame seizures when drugs fail?
- Can a High-Fat diet and therapy tame seizures in rare childhood epilepsy?
- Zapping the brain without surgery: a new hope for Tough-to-Treat epilepsy
- Nerve block may cut opioid needs after epilepsy device surgery