New 'Irregular' pulse may ease shingles nerve pain better than standard treatment
NCT ID NCT07208032
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study compares two types of pulsed radiofrequency treatments for postherpetic neuralgia, the long-lasting nerve pain that can follow a shingles infection. One hundred adults whose pain has not responded to standard care will receive either the regular or a new 'STP' irregular pulse procedure. The goal is to see which method provides better pain relief.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- pulsed radiofrequency procedure
- What this could lead to
- If STP works better, it could offer a more effective, non-drug option for people with stubborn post-shingles nerve pain.
- What could go wrong
- This is a small, early-stage study (100 people) comparing two similar procedures. The new method may not prove significantly better, and results may not apply to everyone with this condition.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Mar 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Patients with Herps Zoster neuralgia lasting more than one month Neck thoracic lumbar ganglion involvement Refractory to conventional therapy Exclusion Criteria: Infection ,tumour at the puncture site Severe cardiovascular or cerebrovascular disease Liver, kidney dysfunction Abnormal coagulation Uncontrolled DM Psychatric diseases Patient refusal
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
2 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Medical research ethics committee
Sohag, Sohag Governorate, 82511, Egypt
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Medical research ethics committee
Sohag, Egypt
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