INSOMNIA

This study tested a prevention program using nurse-led coaching to help people with low income or education who were having early signs of insomnia. The goal was to stop their sleep problems and depression from getting worse. 167 adults took part, and the program focused on chang…

This study tested a new cognitive training program (COGMUSE) for autistic adults who also have insomnia. Twelve participants played brain-training games at home for 60 minutes, three times a week, for six weeks. They wore a watch-like device to track sleep and movement and filled…

This study tested a smartphone app that delivers a brief behavioral therapy for insomnia in adults aged 60 and older. 270 participants used either the app or received online sleep health education. The goal was to see if the app could reduce insomnia symptoms and improve sleep qu…

This study tested a brief cognitive-behavioral therapy (CBT) program to help older adults (55+) safely reduce or stop taking benzodiazepines, which are often used for sleep or anxiety but can be risky with age. Seventeen participants received up to three CBT sessions alongside th…

This study tested whether the sleep drug suvorexant could reduce insomnia severity and improve metabolic health in 31 midlife women (ages 40-65) who had both insomnia and early signs of metabolic syndrome. Participants took the medication for 4 weeks, and researchers measured cha…

This study tested whether shining low-level laser or LED light on specific hand acupoints can help people with insomnia relax and sleep better. 120 participants received either real or sham light therapy, and researchers measured heart rate variability and meridian energy before …

This study looked at whether cognitive behavioral therapy (CBT) for insomnia can reduce pain and improve sleep in women with fibromyalgia. 131 women with both conditions took part. The goal was to see if treating sleep problems could also help with pain and brain changes linked t…

This study tested if a type of talk therapy called Acceptance and Commitment Therapy (ACT) can help people with insomnia, without adding the usual sleep tips like keeping a strict bedtime. 93 adults with insomnia were randomly assigned to either 7 weeks of ACT or a waitlist. The …

This early-stage study tested a new insomnia drug called HEC83518 in 57 healthy Chinese adults aged 18-45. The main goal was to check safety and how the body processes the drug, not to treat insomnia directly. Participants took multiple doses, and researchers monitored side effec…

This small study tested whether cannabis oil can improve sleep in people with major depression and insomnia. 14 adults took part. The goal was to see if a larger study is possible and to compare different types of cannabis oil. The study is now complete.

This study tested whether a new drug, tasipimidine, helps people with insomnia fall asleep faster and stay asleep longer. 190 adults with insomnia took either the drug or a placebo for 3 nights in a sleep clinic, with some continuing for 4 more weeks at home. Researchers used sle…

This study tested a non-invasive brain stimulation method called tDCS in 320 adults with depression, schizophrenia, OCD, anxiety, or insomnia. Participants received the stimulation while researchers measured symptom changes using standard rating scales. The goal was to see if tDC…

This study tested whether a single online sleep education session, with or without extra coaching, could help young adult cancer survivors (ages 20-39) sleep better. 56 survivors who had finished active cancer treatment took part. The program aimed to reduce insomnia severity and…

This study tested two types of therapy for insomnia in 134 people who were also being treated for alcohol use disorder. The goal was to see if improving sleep could also help reduce drinking. Participants received either a behavioral sleep treatment or a control therapy, and rese…

This study tested a special sleep therapy program, called Sleep-SMART, for older veterans who have both mild memory problems and trouble sleeping. The program adds memory-support strategies to standard insomnia therapy to help veterans learn and stick with the treatment. Thirty v…

This study tested if an app that teaches better sleep habits could help people with chronic pain and insomnia during a 4-week rehab program. 105 adults took part. The goal was to see if the app improved sleep more than rehab alone.

This study tested whether a guided meditation called yoga nidra can help people who have experienced trauma and struggle with insomnia and PTSD symptoms. Sixty adults were randomly assigned to a brief or full version of an 8-week online program, or a waitlist. Researchers measure…

This study tested an internet-based insomnia treatment program in 1,554 adult survivors of childhood cancer. The goal was to see if the program could improve sleep, thinking skills, and quality of life. Participants used an online cognitive behavioral therapy for insomnia (CBTi) …

This study looked at whether a type of talk therapy for insomnia (CBT-I) can help breast cancer survivors take their daily hormone-blocking pills more regularly. 35 women who had trouble sleeping and often missed their medication took part. The goal was to see if improving sleep …

This study tested whether an internet-based sleep treatment could improve sleep and quality of life in veterans with both COPD and insomnia. Thirteen veterans were randomly assigned to either an online behavioral sleep program or online sleep education. The goal was to see if bet…

This study looked at whether two types of talk therapy—Behavioral Therapy and Cognitive Therapy—can help Gulf War veterans sleep better. Fifty veterans with insomnia took part. The main goal was to see if these therapies reduce insomnia symptoms and improve daily life.

This study tested whether adding acupuncture and yoga to a doctor-supervised medication reduction plan helps older adults (65+) safely lower their use of benzodiazepines and similar drugs for anxiety and insomnia. Over 12 weeks, 23 participants received weekly acupuncture, privat…

This study tested whether a sleep improvement program (CBT-I) could reduce symptoms of depression and anxiety in adults with poor sleep and high emotional distress. 51 participants received six sessions of CBT-I over eight weeks. Researchers used brain scans to see if better slee…

This study tested a sleep medication called lemborexant in 82 adults with liver cirrhosis who had trouble sleeping. The goal was to see if it could improve sleep quality safely. The drug works by blocking wakefulness signals in the brain to promote natural sleep.

This study tested a 6-week sleep program in 200 older adults (ages 60-85) with insomnia to see if it improves thinking, memory, and attention. A small group also had brain scans to check for changes in amyloid plaque, a hallmark of Alzheimer's disease. The goal was to understand …

This study tested whether a daily mix of plant protein and two herbs (ashwagandha and rhodiola) could improve sleep in 100 adults aged 35 to 70 who have trouble sleeping. For 30 days, half took the supplement and half took a placebo. The researchers measured sleep quality with da…

This study tested whether a culturally adapted internet-based cognitive behavioral therapy (iCBT) program could help reduce symptoms of depression, anxiety, insomnia, and trauma in Arabic-speaking refugee and migrant youth aged 15-29. 125 participants were randomly assigned to re…

This study looked at 57 university students with insomnia. It compared two programs: mindfulness-based stress reduction (MBSR) and cognitive-behavioral therapy for insomnia (CBT-I). Both programs aimed to improve sleep and mental health. The researchers expected CBT-I to work fas…

This study tested whether a digital cognitive behavioral therapy program for insomnia (Sleepio) is practical and helpful for people with mild cognitive impairment or mild dementia who also have sleep problems. Thirty participants were enrolled to see if they would stick with the …

This study tested whether taking melatonin before bed can reduce pain and improve sleep in people with chronic low back pain and insomnia. 220 adults aged 18-64 took either melatonin or a placebo for several weeks. The goal was to see if this common, low-risk sleep supplement cou…

This study tested whether a culturally adapted version of Cognitive Behavioral Therapy for insomnia (CBTi) could help Arab adults sleep better. 54 participants were randomly assigned to receive one of two adapted CBTi programs or be placed on a waiting list. The goal was to see i…

This pilot study tested a non-drug device called Bioboosti to see if it could help people with insomnia sleep better. Twenty adults with insomnia used the device, and researchers measured changes in sleep quality and daytime sleepiness using standard questionnaires. The goal was …

This study tested a supplement called Neurexan in 81 adults with short-term insomnia (less than 3 months). Participants took Neurexan or a placebo for 14 days. Researchers measured sleep quality using brain activity monitors and stress levels using ice-water hand immersion tests …

This study tested a cognitive behavioral therapy (CBT) course for insomnia in 73 adults who also have a chronic physical illness like arthritis, heart disease, or cancer. The therapy focused on changing sleep habits and thoughts about sleep. Results showed that the course helped …

This study tested whether suvorexant, an FDA-approved sleep medication, can improve daytime symptoms like thinking, mood, and fatigue in older adults with insomnia. 40 participants took either the drug or a placebo for about 16 days and reported their symptoms using a smartphone …

This study tested whether a simple online self-help program could help people with chronic insomnia stop using sleeping pills like benzodiazepines and Z-drugs. 62 adults who had been taking these medications for at least 3 months and wanted to quit were randomly assigned to eithe…

This study looked at whether a short sleep therapy program (BBTI) helps people with substance use disorders who live in a residential treatment center. About 83 participants wore sleep trackers, completed surveys, and did sleep diaries. The goal was to see if better sleep helps t…

This study tested a new sleep medication called daridorexant in 166 teenagers aged 10 to 17 who have trouble sleeping. The goal was to see if the drug helps them sleep longer and is safe. Participants took the medicine or a placebo, and their sleep was measured in a lab.

This study looked at whether drinking tart cherry juice can improve sleep in older adults with insomnia. Twenty people aged 65 and older with sleep problems drank tart cherry juice for 4 weeks and a placebo for 4 weeks. They wore a sleep monitor and gave blood and urine samples t…

This study tested a personalized brain stimulation technique for people with insomnia. Twenty adults received 10 days of treatment tailored to their brain activity. Researchers measured sleep quality and mood changes to see if this approach could ease symptoms.

This study tested an online program to help cancer patients with insomnia. 348 adults with cancer who had trouble sleeping used a step-by-step website with videos and tools. The goal was to see who benefits from extra help from a professional and what kind of support they need.

This study tested two sleep medications, trazodone and eszopiclone, in 673 veterans with PTSD-related insomnia. The goal was to see if these drugs could reduce insomnia symptoms over 12 weeks. Participants were military veterans aged 18-75 with PTSD and sleep problems. The study …

This study tested whether a headband that senses brain activity (Muse-S) can help midlife women with sleep problems like insomnia. Thirty-one women going through menopause wore the device at home. Researchers measured changes in sleep quality and stress using questionnaires.

This early-stage study tested a new insomnia drug called HEC83518 in 74 healthy Chinese adults aged 18-45. The main goal was to check safety and side effects, not to measure how well it works. Researchers gave single rising doses to see how the body processes the drug.

This study tested whether a single online educational session could improve sleep in cancer survivors who have trouble sleeping. 70 survivors with significant insomnia took part. Researchers measured changes in insomnia severity and mood after 8 weeks.

This study tested a mobile app called SleepFix that delivers behavioral therapy for insomnia in 106 adults with chronic low back pain and poor sleep. The goal was to see if using the app for 3 weeks could reduce how much pain interferes with daily life after 6 weeks. Participants…

This study looked at whether teaching primary care providers about insomnia treatment helps patients sleep better. Researchers compared patients whose doctors received special training to those getting usual care. Participants completed surveys about their sleep, and some had a s…

This study tested a capsule containing highly purified CBD and natural plant compounds (terpenes) to see if it improves sleep in people with chronic insomnia. 125 adults aged 25-70 with long-term sleep problems took the capsule or a placebo. The researchers measured sleep stages …

This study tested whether a medication called solriamfetol, cognitive behavioral therapy for insomnia (CBT-I), or both together can help people with insomnia sleep better and feel less tired during the day. 115 adults with insomnia took part. The goal was to see if staying awake …

This study tested an online sleep program for 20 preschool children with autism who had trouble sleeping. The program taught parents behavioral strategies to improve their child's sleep. Researchers measured changes in sleep habits and quality to see if the program was easy to us…

This study tested whether a noninvasive device that gently stimulates a nerve in the ear (taVNS) could help improve sleep in people with stage I-IV breast cancer. Twenty participants completed the trial, and researchers measured how practical and acceptable the treatment was. The…

This study tested whether suvorexant, a sleep medication, could improve sleep and reduce delirium (sudden confusion) in older adults recovering from heart surgery in the intensive care unit. About 100 patients aged 60 and older received either suvorexant or a placebo for 7 nights…

This study tested a smartphone app called DOZE that helps young adults (ages 18-25) with chronic pain and sleep problems learn skills to manage their symptoms. The app combines sleep medicine with self-management techniques. Researchers measured how well participants used the app…

This study looked at how stress and insomnia influence each other in 36 women aged 20-50. Half had insomnia, half slept well. Researchers measured stress reactions during a driving simulation and tracked sleep afterward. The goal was to understand how emotional stress affects sle…

This study looked at whether treating insomnia can lower the risk of heart disease in people with PTSD. Researchers measured blood pressure, blood vessel function, and other heart risk factors in 140 adults aged 40-59. The goal was to see if improving sleep could also improve hea…

This study looked at 149 adults with high blood pressure and insomnia to understand how poor sleep might increase heart disease risk. Participants received Cognitive Behavioral Therapy for Insomnia (CBT-I) to improve sleep. Researchers measured changes in nighttime blood pressure…

This study looked at how often insomnia occurs in people being treated for psychiatric disorders in hospitals in Switzerland and Germany. Researchers checked 427 patients once to see if they had insomnia and whether age, gender, or type of disorder made a difference. The goal was…

This study looked at how well people think, remember, and feel emotionally about 7 and 24 months after surviving a cardiac arrest outside the hospital. About 200 survivors and a similar group of heart attack patients without cardiac arrest took detailed thinking and memory tests.…

This study looked at how to help busy VA doctors adopt better treatments for three common issues: reducing risky medications in older adults, using blood thinners more safely, and offering talk therapy for insomnia instead of sleep pills. Researchers compared two different suppor…

This completed study looked at how blood sugar levels affect sleep in 30 adults with cystic fibrosis-related diabetes. Participants wore devices at home for 10 days to track glucose and sleep patterns. The goal was to see if this type of remote monitoring is feasible and to gathe…

This study followed over 2,300 adults from urban areas of Chile for one year to learn more about chronic pain and its effects. Researchers measured pain levels, mental health issues like depression and anxiety, and how pain impacted work and social life. The goal was to better un…

This study looked at 171 people with HIV to see if insomnia makes pain worse and increases inflammation. Researchers measured pain sensitivity, sleep patterns, and blood markers. The goal is to confirm that treating insomnia could help reduce pain and inflammation in people livin…