INSOMNIA

This study tests if a digital program for insomnia (dCBT-I) can prevent depression in perimenopausal women with sleep problems. About 230 women will either get the insomnia program or sleep hygiene tips. Researchers will check their mood and sleep every 3 months for 2 years to se…

This study tests whether a mobile app called SleepQ can help adults with insomnia sleep better. About 80 participants will either use the app along with their usual care or just continue their usual care. The study is done entirely from home and lasts 12 weeks, with online check-…

This study tests a special sleep therapy called SleepSMART for veterans who have both insomnia and mild cognitive impairment (MCI). The therapy adapts standard insomnia treatment with extra memory and learning support. Researchers will compare SleepSMART to standard therapy in 15…

This study tests a 10-week telehealth program where parents learn techniques to help their autistic child (ages 3-7) sleep better. About 130 children will be randomly assigned to one of two parent-led approaches. The goal is to reduce insomnia symptoms and improve overall well-be…

This study tests a smart home system that uses lights, sounds, and a phone app to deliver insomnia therapy to older adults at home. The goal is to improve sleep and thinking skills. 180 people aged 65 and older with insomnia will use either the smart system, a sleep app, or sleep…

This study compares the effectiveness and safety of common prescription and over-the-counter sleep medications in 1,200 adults with chronic insomnia. Participants will try different medications over several months to see which provides the best relief with the fewest side effects…

This study tests a two-session, Zoom-based cognitive behavioral therapy program designed for Deaf adults who use American Sign Language. The goal is to change negative beliefs about mental health treatment and encourage participants to seek professional help. Researchers will als…

This study tests whether THC alone or combined with CBD can improve sleep in people with solid organ cancer who have insomnia. About 69 participants will receive either THC, a 1:1 mix of THC and CBD, or a placebo. The goal is to see if these cannabis-based treatments help ease in…

This study tests if facial acupuncture, based on traditional Chinese medicine, can help people with insomnia sleep better. Researchers will enroll 82 people aged 16 to 30 who have poor sleep quality. The treatment aims to improve sleep and reduce anxiety without the side effects …

This study tests whether a self-guided mobile app for cognitive behavioral therapy for insomnia (CBTI) can improve sleep and related issues like depression and PTSD in 144 active-duty service members. Participants use the app for five weeks, and researchers measure changes in sle…

This study tests whether an app-based sleep program can improve sleep in new parents who have insomnia. The program uses cognitive behavioral therapy and meditation over 18 days. About 250 first-time parents with infants aged 4-12 months will participate. The goal is to see if th…

This study looks at whether practicing tai chi can improve sleep in people aged 40 to 69 with mild to moderate chronic insomnia. About 60 participants will be randomly assigned to either a tai chi group or a walking group for 6 weeks. The goal is to see if tai chi leads to better…

This study looks at whether racism-related stress makes it harder for Black adults with insomnia to benefit from a common sleep therapy (CBTi). About 100 Black adults aged 18-65 with insomnia and depressive symptoms will use a digital CBTi program for 6 weeks. Researchers will tr…

This study tests a smartphone app called BELL-001 that plays calming sounds timed to your breathing to help you fall asleep. Forty adults with insomnia will use the app for 12 weeks. Researchers will track sleep quality, mood, and safety to see if this drug-free approach works lo…

This study tests a nurse-led sleep program combined with a health chatbot for adults who have trouble sleeping. About 80 participants will either get the chatbot-assisted program or track their sleep on their own. The goal is to see if the program improves sleep, anxiety, depress…

This pilot study will test an 8-week group mindfulness program for 30 Chinese parents caring for children with autism or ADHD. The goal is to see if the program reduces stress, anxiety, depression, and insomnia. Participants will attend weekly sessions and complete surveys before…

This study tests a psychological program designed to improve sleep quality in female university students aged 18 to 25 who have insomnia. The goal is to see if better sleep helps their thinking skills (like focus and planning) and boosts their academic performance. About 35 parti…

This study tests whether a special type of acupressure, given at times that match the body's natural daily rhythms, can improve sleep in older adults living in nursing homes. Eighty people aged 60 and older will receive either this circadian-based acupressure or a fake version fo…

This pilot study tests whether a headband that plays soft sounds in sync with brain waves can improve sleep for 25 adults with both depression and insomnia. Participants wear the device at home for four weeks, alternating between active and sham stimulation, while tracking sleep …

This study tests whether a special 40 Hz flickering light can improve sleep in people with Parkinson's disease who have insomnia. Thirty participants will use either the flickering light or a regular light for 30 minutes each night for a week. The goal is to see if this simple, n…

This study tests whether wearing blue-blocking glasses at night can help teens aged 12-18 with insomnia or delayed sleep phase disorder. The goal is to see if this simple, drug-free approach improves how fast they fall asleep and boosts natural melatonin. The trial involves 40 pa…

This study will test if a standard 18-day spa program can reduce insomnia. 270 participants will fill out questionnaires about their sleep, fatigue, and well-being before, right after, and 2 months after treatment. The goal is to see if spa therapy offers real, measurable benefit…

This study looks at how poor sleep affects warfighters with PTSD, traumatic brain injury, or chronic stress. It tests a smartwatch that vibrates gently when it detects a nightmare or stress surge during sleep. The goal is to see if this device can improve sleep quality, daytime f…

This pilot study tests a digital behavioral therapy app (SleepFix) with psychologist support for young people aged 16-24 who have insomnia. Forty participants will either use the app or receive online sleep education. The goal is to see if the app is practical and helps improve s…

This study tests whether suvorexant, a medication already used for insomnia, can help Veterans with PTSD and sleep problems better overcome fear responses. About 40 Veterans will take the drug for 7 nights and undergo fear conditioning and extinction tests. The goal is to see if …

This study will test a smartphone app called CONEMO to help adults with depression, anxiety, and insomnia. The app has already shown promise for depression. Researchers will invite 12,400 people from 28 health clinics in Brazil to use the app and track their symptoms. The goal is…

This study tests a non-invasive treatment called remote ischemic conditioning (RIC) for sleep problems in people with Parkinson's disease. 48 participants with insomnia will receive either active RIC (using a blood pressure cuff) or a sham version for 7 days. Researchers will mea…

This study looks at whether a type of talk therapy for insomnia (CBT-I) can also improve metabolic health, including insulin resistance and blood sugar. Twenty adults with insomnia and higher body weight will be randomly assigned to CBT-I or basic sleep tips for 5 weeks. Research…

This study tests whether low-dose laser acupuncture can improve sleep in people with major depression and insomnia. 120 adults will receive 30 laser sessions over six weeks, plus their usual depression medication. Researchers will measure sleep quality, depression levels, and saf…

This study tests a wearable voice-guided therapy for people with both insomnia and sleep apnea. About 361 adults will use a smart eye-mask that talks them through sleep exercises. The goal is to improve sleep quality and help people stick with their CPAP machine.

This study tests whether a 6-week cognitive behavioral therapy program for insomnia (CBT-I) can improve sleep and blood sugar control in adults with type 2 diabetes. Thirty participants aged 40 and older with poorly controlled diabetes and insomnia will be randomly assigned to CB…

This study tests if electroacupuncture (a type of acupuncture with mild electric pulses) can reduce a group of common symptoms—pain, tiredness, sleep trouble, anxiety, depression, and brain fog—in breast cancer survivors. About 228 women who have finished active cancer treatment …

This study tests whether electroacupuncture can improve sleep in people with long-term sciatica caused by a slipped disc. About 114 adults with both conditions will receive either real electroacupuncture or a sham version three times a week for four weeks. Researchers will measur…

This study tests whether a low-level laser applied to specific points on the ear can improve sleep in women with breast cancer who have insomnia. Seventy participants will receive either real or sham laser treatments twice a week for five weeks. Researchers will measure sleep qua…

This study tests whether a small, at-home ear stimulation device can improve sleep quality and reduce stress in health sciences students who have trouble sleeping. Sixty students will either receive active stimulation or a placebo-like stimulation on their earlobe for 3 weeks. Th…

This study tests whether daridorexant, a recently approved insomnia medication, can improve sleep and daytime alertness in smokers who are trying to quit. Poor sleep is a major reason people relapse when quitting smoking. The study will involve 44 adult smokers who will take the …

This study tests a 6-week face-to-face cognitive behavioral therapy for insomnia (CBTi) in 770 young people aged 12-24 in Hong Kong who have moderate mental distress and poor sleep. Participants are split into groups that either get the therapy right away or wait. The goal is to …

This study tests a special type of acupuncture (dense cranial electroacupuncture plus body acupuncture) in 148 teens aged 15-22 who have mild to moderate anxiety or depression. Participants will receive either the real treatment or a sham version twice a week for 8 weeks. The goa…

This study tests a new approach for people with severe, long-term insomnia that hasn't improved with standard treatments. Researchers will give a mild anesthetic to help patients sleep naturally and track sleep quality and safety over time. The goal is to see if this method can p…

This study tests whether daridorexant, a sleep medication, can improve both insomnia and depression symptoms in people with major depressive disorder. About 134 adults with stable depression and insomnia will receive either the drug or a placebo for three months. Researchers will…

This study tests whether a traditional Chinese herbal paste (Ning Shen Dan Xiang) with donkey-hide gelatin can improve sleep quality in adults with chronic insomnia. Sixty participants will take the paste twice daily for 8 weeks and complete sleep questionnaires. The goal is to s…

This study will test a new, easy-to-follow sleep hygiene education program for adults with insomnia. Ten participants will learn simple habits and techniques to improve their sleep. The goal is to see if this program can reduce insomnia symptoms and improve daytime energy and moo…

This study tests a smartphone app called BELL-001 that plays personalized sounds to help people with insomnia relax and fall asleep. About 114 adults with insomnia will use either the active app or a sham (fake) version for 4 weeks. The goal is to see if the app improves sleep qu…

This study tests if a brief, phone-delivered insomnia treatment (BBTI) can improve sleep and thinking in older adults with HIV compared to a mindfulness approach. 214 participants aged 50+ with insomnia will complete 4 weeks of therapy and be followed for a year. The goal is to s…

This study tests whether smelling certain essential oils (aromatherapy) can safely improve sleep in elderly women (aged 60+) who have trouble sleeping while in the hospital. 64 participants will receive either real aromatherapy or a placebo, and their sleep quality will be measur…

This study tests whether simple changes to the bedroom environment and basic sleep tips can improve sleep in older adults (65+) who live alone, have memory concerns, and struggle with insomnia. Over 8 weeks, researchers will visit participants' homes to make agreed-upon adjustmen…

This study looks at whether a brief behavioral therapy for insomnia (BBTI) can improve sleep in people who have lost a loved one and now have trouble sleeping. About 58 adults who have been grieving for at least 6 months and have insomnia will take part. They will either receive …

This study tests whether a special sleep therapy (CBT-I) delivered over video calls can help adults with ulcerative colitis who also have insomnia. About 20 people will take part in 5 therapy sessions and complete online sleep diaries and questionnaires. The goal is to see if the…

This study tests a new insomnia drug, APSTZD, to see if it helps people stay asleep. About 222 adults with chronic insomnia will receive either APSTZD, an active comparator, or a placebo for 6 weeks. The main goal is to measure how much time they spend awake after falling asleep,…

This pilot study aims to understand the brain mechanisms behind insomnia by testing a drug that may reduce overactivity in a specific brain region during sleep. Fifteen adults with insomnia will receive the drug and a placebo in random order. The main goal is to measure brain wav…