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Sleep drug may help veterans erase fear memories in PTSD

NCT ID NCT06788522

First seen Nov 10, 2025 · Last updated May 25, 2026 · Updated 23 times

Summary

This study tests whether suvorexant, a medication already used for insomnia, can help Veterans with PTSD and sleep problems better overcome fear responses. About 40 Veterans will take the drug for 7 nights and undergo fear conditioning and extinction tests. The goal is to see if blocking a brain chemical called orexin can improve how the brain unlearns fear, which could lead to better PTSD treatments.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ralph H. Johnson VA Medical Center, Charleston, SC

    Charleston, South Carolina, 29401-5703, United States

    Contact Email: •••••@•••••

  • San Francisco VA Medical Center, San Francisco, CA

    San Francisco, California, 94121-1563, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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