University Of Washington

This study tested whether adding a clinical pharmacist to the care team could reduce medication-related problems for patients moving from a hospital to a skilled nursing facility. Over 1,000 adults participated. The pharmacist reviewed medications and coordinated with the nursing…

This study tested whether giving a drug called erythropoietin (Epo) to extremely premature babies (born at 24-27 weeks) could lower their risk of death or severe brain problems later in childhood. Over 900 babies received either Epo or a placebo within their first day of life. Th…

This study tested a combination of a targeted drug (brentuximab vedotin) with standard chemotherapy (ifosfamide, carboplatin, etoposide) in 45 people with Hodgkin lymphoma that had returned or wasn't responding to treatment. The goal was to find the safest dose of the new drug an…

This pilot study tested whether giving a combination of immunotherapy (pembrolizumab) and chemotherapy before surgery can improve outcomes for people with rare types of muscle-invasive bladder cancer. The study enrolled 17 participants with stage II or IIIA bladder cancer that ha…

This study tested whether giving deworming medicine (albendazole) to everyone in a community for three years can stop the spread of soil-transmitted worms, which infect over 1.5 billion people. Over 350,000 people in India, Malawi, and Benin took part. The goal was to see if comm…

This study tested the drug nivolumab in 20 adults with blood cancers (like lymphoma, leukemia, or myeloma) that returned or did not respond after CAR T-cell therapy. Nivolumab is an immunotherapy that helps the body's immune system attack cancer cells. The goal was to see if it c…

This study tested whether a team-based care model (Collaborative Care) can effectively treat both opioid use disorder and mental health conditions like depression or anxiety in primary care clinics. 254 adults with opioid use disorder and a mental health condition took part. The …

This study tested a new treatment for men with prostate cancer that stopped responding to standard hormone therapy. The approach used high doses of testosterone along with a drug called olaparib to damage cancer cells' DNA and make them die. 36 men took part, and researchers meas…

This study tested a combination of three drugs (mosunetuzumab, polatuzumab vedotin, and obinutuzumab) in 42 people with untreated slow-growing B-cell non-Hodgkin lymphoma. The goal was to see how many patients achieve complete remission (no cancer detectable). The drugs work by h…

This study tested a new insulin dosing calculator for adults with type 2 diabetes when they are admitted to the hospital. The goal was to see if the calculator could help control blood sugar without causing dangerously low levels. 38 participants received their first insulin dose…

This study tested whether a culturally tailored diabetes education program, called Compañeros en Salud, combined with a continuous glucose monitor (CGM) helps Latinx adults with type 2 diabetes better control their blood sugar. 120 participants were randomly assigned to receive t…

This pilot study tested whether giving a mix of glucose, insulin, and potassium (GIK) during abdominal surgery can reduce serious complications in patients who do not have diabetes. About 106 adults took part to see if the treatment is practical and safe. The goal is to plan a la…

This study tested whether giving TB prevention medicine in the community with fewer refill visits helps more people finish their treatment compared to the usual monthly clinic visits. 301 adults in South Africa who were at risk for TB took part. The goal was to see if the communi…

This project aimed to make HIV prevention services, including PrEP pills, easily available to young women when they visit family planning clinics in Kenya. Over 25,000 women took part. The goal was to see if offering HIV risk screening and PrEP at these clinics could help more wo…

This study tested whether following a Mediterranean-style diet could help prevent repeat episodes of diverticulitis, a painful digestive condition. 71 adults who had recently recovered from diverticulitis were randomly assigned to either a Mediterranean diet or standard fiber gui…

This study looked at different ways to help young women in South Africa, ages 18-25, take their daily HIV prevention pill (PrEP) consistently. The goal was to find the best support strategies to keep them protected from HIV. 360 women took part in the study, which tested a step-b…

This study tested whether taking a weekly dose of the antibiotic doxycycline can prevent bacterial sexually transmitted infections (STIs) in cisgender women who are already taking daily PrEP to prevent HIV. The study involved 60 women aged 18-30 in Kisumu, Kenya, and focused on m…

This study tested a pop-up clinic inside a van for women who inject drugs and exchange sex in north Seattle. The goal was to see if offering HIV prevention pills, addiction medications, and quick STI testing in a convenient location would help more women start and stay on these t…

This study looked at how safe and effective a daily HIV prevention pill (TAF-FTC) is in 54 Kenyan cisgender women. Participants took different numbers of doses each week to mimic real-world use. The goal was to measure drug levels in the blood and tissues, helping doctors better …

This study tested a web-based program for college women who have experienced sexual assault and drink heavily. The program teaches skills to manage emotions and cope with distress, aiming to reduce drinking. About 200 women from the University of Washington took part. The goal wa…

This study tested two mobile health (mHealth) strategies to help people with schizophrenia manage their symptoms. 299 participants used smartphone tools to track and improve issues like depression, anxiety, and insomnia. The goal was to see if these digital tools could make a rea…

This study tested whether using virtual reality (VR) can lower the pain people feel from brief, hot sensations. 24 healthy adults received short, painful-but-tolerable heat pulses on their skin, sometimes while wearing a VR headset and sometimes without. They rated their pain eac…

This study looked at whether adding acupuncture and acupressure to oral cryotherapy (sucking on ice chips) can better prevent or reduce nerve pain caused by oxaliplatin chemotherapy in people with gastrointestinal cancers. 78 participants were split into two groups: one received …

This study tested a trauma-focused therapy (TF-CBT) for young people aged 8 to 19 who had experienced trauma and had PTSD symptoms. The therapy was delivered in schools to make it easier for students to get help. Researchers also tested a strategy to help school clinicians adopt …

This study tested if using buffered lidocaine (a less acidic numbing medicine) reduces pain during prostate biopsy. 350 men scheduled for a biopsy rated their pain after the injection. The goal was to see if this simple change, already used in other procedures, could make the exp…

This study tested a new, non-invasive treatment to improve hand and arm function in people with spinal cord injuries. Fifteen adults with chronic cervical spinal cord injury received either electrical stimulation of the spinal cord combined with physical therapy, or physical ther…

This study tested a program called PRISM to help adults with congenital heart disease build resilience and manage stress. Researchers enrolled 78 participants to see if the program was feasible and if it could improve resilience scores. The goal was to support emotional well-bein…

This study tested whether a pharmaceutical-grade psilocybin (from magic mushrooms) combined with group therapy is safe and helps reduce anxiety and depression in people with metastatic cancer. 55 participants received the drug in a small group setting. The goal was to see if the …

This study tested whether a single online session called SPARK Coping could help college students who have early signs of psychosis feel less distressed and more open to seeking treatment. About 50 University of Washington students took part, filling out surveys at the start and …

This study tested whether helping people feel less lonely can reduce their risk of misusing prescription opioids. Researchers worked with 102 adults who were taking opioids long-term for chronic pain and felt lonely. Participants received psychological therapy and social support …

This study tested a web-based hypnosis app called Rose in 100 adults with chronic pain (including low back pain) over 8 weeks. Participants used the app and reported on pain, satisfaction, and interest in continued use. The goal was to see if the app is user-friendly and effectiv…

This study tested a text-message chatbot called Cecebot to see if it helps breast cancer survivors with insomnia. The chatbot combined sleep therapy and physical activity tips. The study included 60 women with stage I-III breast cancer who had trouble sleeping for at least 3 mont…

This study tested a new type of prosthetic socket (called a subischial socket) in 84 adults with a leg amputation who have limited mobility. The goal was to see if this socket improves comfort, how long it can be worn, and overall quality of life compared to the standard socket. …

This study looked at whether walking in nature can help reduce depressive symptoms in college students more than walking in a city. 138 students with mild to moderate depression were randomly assigned to take 30-minute walks twice a week for three weeks in either a natural settin…

This study tested a comprehensive self-management program for people with inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease. The program included eight sessions covering topics like symptom tracking, relaxation, diet, and pain management. Research…

This study tested whether acupuncture can reduce pain in people with long COVID. 93 adults were randomly assigned to receive either 8 acupuncture sessions or their usual care. Participants completed surveys about pain and daily activities over 5 months. The goal was to see if a l…

This study looked at ways to help people recovering from a stroke use a CPAP machine for sleep apnea. About 36 stroke survivors took part. The goal was to see if special support during rehab could increase nightly CPAP use and improve recovery.

This study tested a mobile app designed to help people with chronic pain manage their symptoms and improve daily life. 108 adults with chronic pain used the app, which also offered an optional activity tracker. The goal was to see if the app is easy to use and can reduce how much…

This study tested a program where pregnant people could text with a trained peer mentor for mental health support. 127 participants were split into two groups: one could text a mentor, the other got automated messages. The mentor group had lower anxiety six weeks after giving bir…

This study looked at whether a second psilocybin-assisted group therapy session is safe and helpful for people with advanced cancer who still had anxiety after their first retreat. Fifteen patients who had only partial relief from their first session took part. The goal was to se…

This study looked at whether three types of cognitive behavioral therapy (CBT) delivered online could help reduce fatigue in people with multiple sclerosis. 21 adults with MS and chronic fatigue tried relaxation training, behavioral activation, or cognitive therapy. The goal was …

This study looked at how feeling discriminated against affects the way seriously ill racial minority patients talk with their doctors and make decisions about their care. Researchers tested a program called PRISM to help these patients build resilience and improve communication. …

This study tested whether oxytocin nasal spray helps people with social anxiety disorder learn safety from watching others. About 120 adults received either oxytocin or a placebo and underwent brain scans. The goal was to see if oxytocin improves the brain's ability to tell threa…

This study looked at how young children with Down syndrome, cerebral palsy, or other motor delays first use mobility devices like a bodyweight support system or a powered chair. Researchers measured how much of a play space the children explored and their muscle activity. The goa…

This study tested a mobile app designed to help caregivers of young adults with early psychosis. The app provides interactive lessons to improve caregivers' knowledge and skills, aiming to reduce family stress and help the young adult get treatment sooner. 60 caregivers in the US…

This study looked at how psychological stress affects the decision to drink alcohol in people who drink regularly. 160 participants were split into four groups, some exposed to stress and some not, and given a choice between alcoholic and non-alcoholic drinks. The goal was to und…

This study aimed to understand how to safely reopen K-5 schools and keep students learning in person during the COVID-19 pandemic. Researchers worked with over 1,000 students, parents, and school staff, focusing on rural Latino communities. They tested a school testing program an…

This study aimed to understand the challenges Spanish-speaking patients face when leaving the hospital for a nursing facility. Researchers interviewed 17 patients and caregivers to identify communication barriers and what helps or hinders a smooth transition. The goal is to use t…

This study looked at how gender-affirming testosterone treatment changes the way the body processes other medications. Researchers measured the levels of a test drug in the blood of 14 transgender adults before and after starting testosterone therapy. The goal was to understand i…

This study tested a new artificial intelligence tool called CBTpro that helps therapists improve their skills in cognitive behavioral therapy for psychosis. Over 600 adults with conditions like schizophrenia or bipolar disorder took part. The goal was to see if the tool could mak…

This study tested whether a special ultrasound technique can measure blood flow in the spinal cord during surgery for acute spinal cord injury. 27 adults with recent injuries took part. The goal was to see if this method works, which could help doctors choose treatments to improv…

This study looked at 112 people to see if brain inflammation (called gliosis) affects weight loss and regain. Researchers used MRI scans to compare people who lost weight through diet or surgery. The goal was to learn why weight often returns after dieting and how the brain might…

This study looked at whether being in a virtual reality (VR) environment affects how well people remember words. Twenty healthy adults from a university took part. They learned some words while in VR and others during a regular distraction. The main goal was to see if VR changes …

This study looked at whether a digital training platform could help clinicians effectively use a smartphone app called FOCUS to support people with serious mental illness, such as schizophrenia, bipolar disorder, or major depression. 191 adults used the app and received coaching …

This study tested a short home-visiting program for birth parents whose young children (ages 1-5) had been returned to them after foster care. The goal was to see if the program could improve parenting skills and reduce the chance of children being removed again. 264 parents took…

This study tested whether health messages delivered through online modules and text messages are easy to use and acceptable for young adults aged 18-24 who drink heavily. 35 participants were randomly assigned to receive the messages or just take surveys. The main goal was to see…

This study tested whether an AI scribe that listens to doctor-patient conversations can reduce doctor burnout and improve patient satisfaction. 139 doctors and advanced practice providers from primary care, oncology, and urology were randomly assigned to use the AI scribe or cont…

This study worked with 13 formerly incarcerated parents and their children's caregivers to adapt a parenting support program. The goal was to improve parents' well-being and parenting skills, and to prevent problems from passing to the next generation. Re-entry navigators with li…

This study tested a mentoring program for women working in the sheet metal trades. The goal was to see if having a mentor could reduce stress, prevent injuries, and improve job satisfaction. About 96 women took part, including both new apprentices and experienced journey-level wo…

This study looked at how two hormones that rise during pregnancy—estradiol and cortisol—affect the way the body breaks down THC, the main active ingredient in cannabis. Fourteen healthy women of childbearing age took part. Researchers measured THC levels in the blood after taking…

This study looked at how fear and reward systems in the brain affect recovery from PTSD and alcohol use after sexual assault. Researchers studied 82 women who had experienced sexual assault and had both PTSD and heavy drinking. The goal was to learn more about these conditions to…

This study looked at why walking takes more energy for children with cerebral palsy (CP). Researchers measured oxygen use in 34 kids aged 8-17 while they walked on a treadmill with and without support. The goal was to understand the underlying causes of high energy cost, which co…

This study tested whether immersive virtual reality affects memory in healthy adults. 16 participants from a university psychology course completed word recall tasks while using VR. The goal was to see if VR could distract people and change how well they remember information.

This study collected blood, urine, and kidney tissue samples from 90 adults hospitalized with COVID-19 who also had or were at risk for acute kidney injury. Researchers aimed to build a detailed database of these samples to better understand how COVID-19 affects the kidneys. The …

This study looked at how alcohol changes attention in young adults aged 21-25 who drink regularly. Participants completed simple phone-based games to measure focus before and after drinking alcohol, both in a lab and during their daily lives over eight weekends. The goal was to u…

This study looked at how gender-affirming estrogen therapy changes the way the body processes other medications. Twenty-two transgender adults who were not yet on estrogen took part. Researchers measured how two common drugs (midazolam and digoxin) were handled before and after s…

This study looked at how the brain naturally reduces pain when a person feels two painful sensations at the same time. Researchers wanted to see if paying attention to one pain can help turn down the other. Twenty-four healthy University of Washington students took part, rating t…