New drug combo shows promise for untreated lymphoma patients

NCT ID NCT05169658

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a combination of three targeted drugs (mosunetuzumab, polatuzumab vedotin, and obinutuzumab) in 42 people with untreated slow-growing B-cell non-Hodgkin lymphoma. The goal was to see how many patients achieved a complete response (no cancer detected). The drugs work by helping the immune system attack cancer cells or by delivering chemotherapy directly to them. This approach aims to control the disease without the need for lifelong medication, though ongoing monitoring is still required.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

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