University Of Washington

This study tests whether combining an immunotherapy drug (pembrolizumab) with chemotherapy (carboplatin) can prevent ovarian, fallopian tube, or peritoneal cancer from progressing after a blood test shows it may be coming back. About 22 adults whose cancer had previously responde…

This study tests whether using simple, fast tests at the clinic can help people with HIV stick to their medication and keep the virus at undetectable levels. About 539 people starting HIV treatment in South Africa will get either standard care or these quick tests. The goal is to…

This study looks at whether using home blood pressure readings to guide treatment can reduce sudden drops in blood pressure during dialysis. About 200 adults with end-stage kidney disease on dialysis will take part. Researchers will compare targeting a home blood pressure below 1…

This study tests a program that combines a patient navigator, a smartphone app, and small rewards to help people who use both opioids and methamphetamine stay connected to addiction treatment after leaving the hospital. Forty adults who started buprenorphine while hospitalized wi…

This study tests a DNA vaccine called STEMVAC in people with stage IV non-small cell lung cancer. The vaccine gives the body instructions to make parts of five proteins found on lung cancer cells, helping the immune system recognize and attack them. The trial includes 5 participa…

This study tests a program called Journey of Transformation for Native youth in tenth grade at an off-reservation boarding school. The goal is to see if it can delay or reduce tobacco, alcohol, and other drug use, and improve sexual health. About 182 students take part, and the p…

This early-phase study tests whether MDMA (the drug in ecstasy) combined with talk therapy can help people with pathological narcissism. Twelve adults will receive the treatment during three monthly sessions and be followed for six months. The goal is to see if symptoms improve a…

This study looks at whether a chatbot called Cecebot can help breast cancer survivors with insomnia sleep better. About 60 women with stage I-III breast cancer who have trouble sleeping will use the chatbot, which sends text messages with tips from cognitive behavioral therapy an…

This study looks at ways to help women who have experienced sexual assault and are dealing with both PTSD and heavy alcohol use. Researchers are testing different treatment approaches to see which works best for reducing symptoms and improving recovery. The study involves 82 wome…

This study was designed to test a new therapy model called 'Connections' for teens and young adults (ages 13-30) who have had suicidal thoughts or attempts in the past year but do not need immediate crisis care. The approach combines a special counseling style (Aeschi Model) with…

This study compares surgery (colectomy) to the best medical treatments for people whose diverticulitis limits their quality of life. About 255 adults with at least one confirmed episode of diverticulitis are taking part. The goal is to see which approach better improves daily liv…

This study looks at whether sending caring text messages to stressed or distressed veterans and service members can reduce their emotional pain and lower suicide risk. Over 500 participants will receive either caring texts plus helpful resources, or just the resources alone. The …

This study compares two treatments for people with a type of bladder cancer that keeps coming back: medication placed directly into the bladder or surgery to remove the bladder. Researchers want to see which option gives patients a better quality of life. About 570 adults with hi…

This study tests a new approach to help clinics in Mozambique better manage mental health care. Researchers want to see if a step-by-step improvement plan can help more patients get diagnosed, stay in treatment, and feel better. About 155 patients will take part, and the study fo…

This study looks at whether web resources and personalized outreach can help people who have a high inherited risk for cancer follow their doctor's recommended screenings and surgeries. About 900 adults with a genetic variant linked to cancer will take part. The goal is to improv…

This study tests whether a website with educational resources helps people with cystic fibrosis (CF) feel more prepared to discuss lung transplant with their doctors. About 132 adults with CF and low lung function will take part over 6 months. The goal is to reduce the number of …

This study looks at whether advanced MRI scans can help doctors understand the biology of very early breast changes called ductal carcinoma in situ (DCIS), which often show up as calcium spots on mammograms. About 122 women with these suspicious calcifications or recent DCIS diag…