New combo therapy shows promise for tough lymphoma

NCT ID NCT04257578

First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 34 times

Summary

This early-phase study tests whether adding the drug acalabrutinib to a type of immune cell therapy (CAR T-cells) can safely treat B-cell lymphoma, a cancer of the immune system. About 23 adults with certain aggressive or slow-growing lymphomas will receive the combination. The goal is to see if the drug helps the immune cells work better and reduces side effects.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

Conditions

Explore the condition pages connected to this study.