Immunotherapy drug aims to stop deadly skin cancer's return in high-risk patients
NCT ID NCT03271372
First seen Nov 01, 2025 · Last updated Jun 08, 2026 · Updated 30 times
Summary
This phase 3 trial tests whether the immunotherapy drug avelumab can keep Merkel cell carcinoma from returning in patients whose cancer has spread to lymph nodes and who have already had surgery or radiation. About 100 adults will receive either avelumab or a placebo every two weeks for up to a year. The goal is to see if avelumab helps the immune system attack any remaining cancer cells and improves survival without the cancer coming back.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
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Memorial Sloan Kettering Cancer Center
New York, New York, 10065, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Northwestern University
Chicago, Illinois, 60611, United States
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University of California Irvine Chao Family Comprehensive Cancer Center
Orange, California, 92868, United States
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University of Colorado Cancer Center University of Colorado Anschutz Medical Campus
Aurora, Colorado, 80045, United States
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University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109, United States
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University of North Carolina Lineberger Comprehensive Cancer Center
Chapel Hill, North Carolina, 27599, United States
Conditions
Explore the condition pages connected to this study.