Can MRI spot dangerous breast calcifications without a biopsy?
NCT ID NCT03495011
First seen Jun 25, 2026 · Last updated Jul 22, 2026 · Updated 3 times
Summary
This study looks at whether advanced breast MRI can tell the difference between harmless and dangerous breast calcifications, which are often a sign of very early-stage breast cancer called DCIS. About 122 women with suspicious calcifications or recent DCIS diagnosis will get an MRI before surgery. The goal is to see if MRI features match up with lab tests that show how aggressive the cancer might be, which could lead to better, less invasive diagnosis in the future.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better understand which breast calcifications are dangerous, potentially reducing unnecessary biopsies.
- What could go wrong
- This is an observational study, not a treatment trial. It may not lead to immediate changes in patient care, and results may not apply to all women.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fred Hutch/University of Washington Cancer Consortium
Seattle, Washington, 98109, United States
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