New hope for rare bleeding disorder: emicizumab trial aims to stop bleeds

NCT ID NCT05345197

First seen Nov 06, 2025 · Last updated May 19, 2026 · Updated 25 times

Summary

This study tests a drug called emicizumab to prevent bleeding episodes in people with acquired hemophilia A, a rare condition where the immune system attacks clotting factors. About 51 adults with active bleeding will receive regular emicizumab injections. The main goal is to see if it reduces the number of serious bleeds over 12 weeks.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Bleeding and Clotting Disorders Institute

    Peoria, Illinois, 61614, United States

  • Emory University

    Atlanta, Georgia, 30308, United States

  • Georgetown University

    Washington D.C., District of Columbia, 20007, United States

  • Hemophilia Center of Western Pennsylvania

    Pittsburgh, Pennsylvania, 15213, United States

  • Indiana Hemophilia and Thrombosis Center, Inc.

    Indianapolis, Indiana, 46260, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • Penn Blood Disorders Program, Hospital of the University of Pennsylvania

    Philadelphia, Pennsylvania, 19104, United States

  • Tulane University

    New Orleans, Louisiana, 70112-2632, United States

  • UCSD Hemophilia and Thrombosis Treatment Center

    San Diego, California, 92121, United States

  • UVA Comprehensive Cancer Center

    Charlottesville, Virginia, 22908, United States

  • University of North Carolina

    Chapel Hill, North Carolina, 27514, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

  • University of Vermont Medical Center

    Burlington, Vermont, 05401, United States

  • Versiti Inc.

    Milwaukee, Wisconsin, 53226, United States

  • Washington Center for Bleeding Disorders

    Seattle, Washington, 98101, United States

  • Washington University

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.