Personalized pain therapy: One-Size-Fits-All may be over

NCT ID NCT05699252

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether matching adults with chronic pain to specific psychological treatments—like cognitive behavioral therapy, mindfulness, or hypnosis—based on their personal traits (such as brain activity or thinking patterns) leads to better pain relief. Researchers will study 331 participants to find out which factors predict who benefits most from each therapy. The goal is to move away from a one-size-fits-all approach and toward personalized pain care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Cognitive Behavioral Therapy, Mindfulness-Based Cognitive Therapy, Hypnotic Cognitive Therapy

What this could lead to

If successful, this could help doctors choose the best psychological treatment for each person with chronic pain, improving pain relief for many.

What could go wrong

This is an early-stage study focused on finding patterns, not testing a new treatment. Results may not lead to a simple matching tool, and individual responses vary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Washington, Ninth and Jefferson Building

    Seattle, Washington, 98104, United States

  • VA Puget Sound Health Care System, American Lake

    Tacoma, Washington, 98493, United States

  • VA Puget Sound Health Care System, Seattle Division

    Seattle, Washington, 98108, United States