New drug combo shows promise against Hard-to-Treat prostate cancer

NCT ID NCT05960578

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 27 times

Summary

This study tests whether combining two drugs—golimumab (which reduces inflammation) and apalutamide (which blocks male hormones)—can shrink or slow advanced prostate cancer that no longer responds to standard hormone therapy. Eight men with metastatic castration-resistant prostate cancer took part. The main goal was to see if PSA levels dropped by at least half. This approach aims to control the disease rather than cure it.

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Contacts and locations

Locations

  • Fred Hutch/University of Washington Cancer Consortium

    Seattle, Washington, 98109, United States

Conditions

Explore the condition pages connected to this study.