DEMENTIA

This study tested different doses of nicotinamide riboside (a form of vitamin B3) in 80 people with early Alzheimer's disease. The goal was to find the dose that best boosts brain energy levels without causing side effects. Participants took pills daily for 12 weeks and had brain…

This study tested an experimental drug called XPro1595 in 208 people with early Alzheimer's who also had signs of brain inflammation. The goal was to see if the drug could improve thinking, memory, and daily function compared to a placebo. Researchers also checked for safety and …

This study tested a one-year virtual program for people with dementia and their caregivers. Care coordinators provided monthly video or phone visits to address symptoms, caregiver stress, medications, and care planning. The goal was to reduce emergency room visits and improve qua…

This study looked at whether two different blood thinners—dabigatran and warfarin—could help prevent dementia and memory loss in people over 65 with atrial fibrillation (an irregular heartbeat). About 100 participants were followed for two years with memory tests and brain scans.…

This study tested whether an AI tool called AcceXible can detect early signs of dementia or mild cognitive impairment by analyzing how people describe images. Researchers recorded speech from 273 adults aged 55 and older, including healthy volunteers and those with memory concern…

This study tested a new blood test that uses a special chip to measure two key markers (amyloid-β and PKC) in red blood cells to help diagnose Alzheimer's disease. Researchers collected blood and urine samples from 150 people—50 with Alzheimer's, 50 with other brain diseases, and…

This study tested a tool called eRADAR that uses information already in a patient's electronic health records to identify people who might have undiagnosed dementia. Over 1,200 adults without a prior dementia diagnosis took part. The goal was to see if this low-cost method could …

This study tested a new blood test to see if it can help diagnose Alzheimer's disease. Researchers measured two specific markers in the blood of 200 people, including those with Alzheimer's and healthy volunteers, over 24 months. The goal was to see if these markers can reliably …

This study looked at whether a blood test can accurately diagnose Alzheimer's disease, instead of the usual spinal fluid test. Researchers tested 342 adults visiting memory clinics. They measured certain proteins in the blood and compared results to standard diagnostic methods. T…

This study tested whether an 8-week course led by a robot (called Kebbi) could help prevent or delay cognitive decline in older adults. 80 people aged 65 and older with mild memory problems took part. The robot taught lessons and led interactive games to boost thinking, mood, and…

This study tested whether adding horses to memory workshops helps people with mild to moderate dementia. 36 older adults took part in either horse-assisted memory workshops, traditional memory workshops, or no extra activities for 8 weeks. Researchers measured changes in thinking…

This study tested whether methylphenidate (Ritalin), a drug used for ADHD, can improve walking problems and attention in people with advanced Parkinson's disease. 69 participants with severe gait freezing took either the drug or a placebo for 3 months. Researchers measured steps,…

This study tested a personalized activity plan for 61 people with early-stage dementia. The goal was to see if meaningful activities could help maintain thinking skills, memory, and mood as the disease progresses. Researchers worked directly with participants to design activities…

This study developed and tested a mobile app to help people caring for a loved one with dementia. 59 caregivers in Singapore used the app for one month or were placed on a waiting list. The goal was to see if the app could reduce feelings of depression and burden, and improve kno…

This study tested a medicine called BXCL501 for calming sudden episodes of agitation in people with dementia. 151 participants took the medicine or a placebo as needed over 12 weeks. The goal was to see if the medicine safely reduces agitation symptoms like tension and hostility.

This study tested whether a gentle, non-invasive brain stimulation device used at home could help people with mild to moderate Alzheimer's disease. One hundred older adults used the device for 30 minutes a day, five days a week, for six months. The goal was to see if it improved …

This study tested whether a non-invasive treatment called repetitive transcranial magnetic stimulation (rTMS) can improve memory and thinking in older veterans with mild cognitive impairment or dementia. Researchers measured changes in memory tests and blood markers after treatme…

This study tested whether a virtual reality program featuring nostalgic scenes could improve emotional well-being and thinking skills in older adults (65+) with mild memory problems. Participants used VR headsets twice a week for about 20 minutes, reliving familiar experiences. R…

This pilot study tested a program called Shed-MEDS in 18 people with dementia living in assisted living facilities. The goal was to safely reduce or stop medications that may be unnecessary or harmful, based on medical guidelines and personal preferences. Researchers tracked how …

This study tested whether adding game-like features to a visual mapping app helps people with mild-to-moderate Alzheimer's or related dementias stay engaged and improves their quality of life. Sixty participants (each with a primary caregiver) used either the gamified app or the …

This study tested new swallowing exercises for people with Alzheimer's disease or other dementias who have trouble swallowing. The goal was to reduce the amount of food or liquid left in the throat after swallowing, which can lead to pneumonia. 76 patients and their caregivers to…

This study tested a home-based device called Care4AD to help caregivers of people with Alzheimer's or dementia. The goal was to see if it could reduce caregiver stress and burden over three months. The study involved 33 caregivers and older adults with mild to moderate dementia.

This study tested a mobile app designed to support informal caregivers of people with dementia. 75 caregivers used the app daily for two months, and researchers measured changes in their stress levels, quality of life, and the dementia patient's symptoms. The goal was to see if t…

This study tested a program called IPPI for 108 nursing home residents with dementia and signs of distress or depression. Care partners offered two short, personalized activities each week for six months. The goal was to see if the program was practical and if it helped improve m…

This study tested a program called MEMORI Corps, where trained volunteers aged 55+ spend time with people who have dementia, doing fun and meaningful activities together. The goal was to see if this companionship could reduce loneliness and improve quality of life for people with…

This study tested a 6-week online workshop for 109 family caregivers of people with dementia. The workshop taught caregiving skills and ways to manage stress and difficult emotions. Caregivers could join from home at any time and chat with other caregivers and trained leaders. Th…

This study looked at whether digital or physical brain exercises could help older adults with mild to moderate Alzheimer's disease. Over 500 people in Portugal took part. The goal was to see if these activities could improve memory, thinking, mood, and quality of life.

This study tested a hearing care program for older adults with dementia and hearing loss. Speech-language pathologists provided the care instead of audiologists. The goal was to see if this approach could reduce troubling symptoms like agitation and improve quality of life. 77 pe…

This study tested whether a smartwatch and weekly health coaching could help people caring for a loved one with dementia improve their sleep, activity, and mood. Twenty-one caregivers wore an Apple Watch to track their sleep and activity, received personalized feedback through a …

This study tested a non-invasive device that gently stimulates a nerve in the ear (taVNS) to see if it could improve thinking, sleep, and reduce inflammation in older adults with frailty. 80 people over age 60 without dementia took part, receiving either active or sham stimulatio…

This study tested whether structured music improvisation sessions led by professional musicians could improve the mental and physical health of older adults with dementia. Seven participants with mild to moderate dementia took part, along with their caregivers. The goal was to se…

This study tested a support program for people with dementia living at home. The program trained nurses to focus on what the person can still do and involved family caregivers in conversations about daily choices. 12 people with dementia, 14 caregivers, and 33 nurses took part. W…

This study looked at whether using adult day services (like adult day care) can lower stress in Black caregivers of family members with dementia. Researchers measured stress through surveys and saliva samples from 42 caregivers. The goal was to see if taking a break from caregivi…

This study looked at whether acupuncture and acupressure can improve thinking skills and quality of life in older adults with mild to moderate dementia. 236 people aged 65 and older from nursing homes took part. They received either routine care, acupuncture, acupressure, or both…

This study looked at how visits from therapy animals affect people with moderate to severe dementia living in nursing homes. Researchers observed changes in mood, behavior, and communication during animal visits compared to other activities. The goal was to see if animal-assisted…

This study tested a tablet-based exercise program called KOKU-LITE, designed to help people with dementia improve balance and prevent falls. Researchers worked with 60 participants, including people with dementia and their caregivers, to see if the program was easy to use and hel…

This study tested a dementia care program delivered by phone and web, called the Care Ecosystem, in 6 health systems across the U.S. Over 1,200 people with dementia and their caregivers took part. The program used trained navigators supervised by dementia experts to improve care …

This study tested a telehealth program that combines music therapy with social work support for older adults living at home. Twenty people aged 65 and older, some with dementia, took part in video sessions to see if it improved their well-being, thinking skills, and feelings of l…

This study explored whether smart electric vehicles can detect walking problems and help improve balance in people with Parkinson's disease or dementia. 120 participants aged 60-85 with mild to moderate walking issues took part. The main goal was to see if the vehicles could assi…

This study tested whether special snacks that change from one texture to another (like a solid that melts) could help people with dementia eat more and improve their nutrition. Ten people with dementia living at home tried these snacks for a few weeks. The goal was to see if the …

This study tested whether a digital cognitive behavioral therapy program for insomnia (Sleepio) is practical and helpful for people with mild cognitive impairment or mild dementia who also have sleep problems. Thirty participants were enrolled to see if they would stick with the …

This study tested an upgraded smart cloth home care system with a family caregiver app for people with dementia and their families. 60 people with dementia and their caregivers in Northern Taiwan took part. The goal was to see if the system could improve caregiver preparedness, m…

This study tested a new in-home technology designed to help Spanish-speaking caregivers of people with dementia, Alzheimer's, or mild cognitive impairment. Six caregivers used the system for six months to see if it could lower their stress, anxiety, and loneliness. The goal was t…

This study tested a website called WeCareAdvisor that helps people caring for a loved one with dementia. The tool gives tips and strategies to manage challenging behaviors like aggression or wandering. Researchers wanted to see if it could lower caregiver stress and boost their c…

This study tested whether wearable devices like Apple Watches could help reduce anxiety, burden, and loneliness in people caring for a family member with dementia or mild cognitive impairment. 63 caregivers in the U.S. used the technology at home for 6 months. The goal was to see…

This study tested a virtual group therapy program called Cognitive Stimulation Therapy (V-CST) for people with mild to moderate dementia. 133 participants were randomly assigned to either join the online therapy or receive usual care. The goal was to see if the therapy could slow…

This study tested whether a community health worker (CHW) program could help people with dementia and their caregivers after a hospital stay. Researchers enrolled 34 patients and their caregivers to see if the program was feasible and acceptable. The goal was to improve caregiver…

This study tested a distance-learning program that trains family caregivers to reduce care-resistant behaviors in people with Alzheimer's dementia or traumatic brain injury. The program aimed to improve quality of life for both patients and their families. Researchers enrolled 88…

This study tested a special palliative care program for people with late-stage Alzheimer's or related dementias and their family caregivers. The program started during a hospital stay and included caregiver education and support after discharge. Researchers wanted to see if it co…

This study tested whether virtual music therapy with active participation works as well as in-person music therapy for reducing stress in older adults with memory problems. Thirty-two participants from assisted living facilities took part. Researchers measured stress levels, hear…

This study looked at whether playing digital games together in a group could help older adults with early to moderate dementia. Twenty-four participants played games twice a week for 20 weeks. Researchers measured changes in thinking, mood, and behavior before and after the progr…

This study tested whether a long-term exercise program could help people with dementia living in nursing homes maintain their ability to do daily tasks like bathing and dressing. 140 participants were split into an exercise group and a social activity group. The goal was to see i…

This study looked at whether giving dementia patients a robotic pet (like a robotic cat or dog) during their hospital stay could improve their well-being. 106 patients aged 65 and older took part. Researchers tracked things like confusion, falls, and use of calming medications to…

This study looked at whether listening to emotionally meaningful music can improve mood and alertness in people with moderate to severe Alzheimer's disease. Ten participants were exposed to special music and a control condition. Researchers measured changes in overall well-being …

This study tested a web-based app called Gotcha! that helps people with mild-to-moderate dementia practice remembering names of people they know. 48 participants used the app at home for about 30 minutes each day over 6 weeks. The goal was to see if the app could improve name rec…

This study tested a video-based program called Tele-STELLA that helps family caregivers of people with Alzheimer's or related dementias. The program connects caregivers with a guide to find ways to reduce upsetting behaviors in their loved ones. The goal was to lower caregiver st…

This study tested whether weighted blankets can reduce agitation and other behavioral symptoms in people with dementia. Thirty patients from hospital and hospice settings participated. Researchers measured changes in agitation and overall symptom burden using standard scales. The…

This study tested an online platform called LifeBio Memory that helps people with dementia and their caregivers share and record life stories. The platform uses machine learning to turn speech into text, making it easier to create personalized life story materials. 234 residents,…

This study tested a new website tool called WeCareToFeedDysphagia to see if it helps reduce stress for people caring for a loved one with dementia and trouble swallowing. 80 caregivers took part, with some getting access to the tool and others getting standard support. The goal w…

This study tested whether starting cognitive training early in the hospital and continuing it at home for 12 weeks could improve thinking and memory in older adults (65+) who experienced delirium. 283 participants were randomly assigned to receive the training or usual care. The …

This study looked at whether a 90-minute gaming-based education program could improve how healthcare students think and feel about people with dementia. About 400 students took part in a single session that included a lecture, a game called N-impro, and short dramas. Researchers …

This study tested whether a special pain assessment tool (PAINAD) helps emergency room staff better manage pain in older adults with dementia who have hip pain. Researchers looked at how often the tool was used and whether it led to faster or better pain relief. The goal was to i…

This study followed 229 adults over age 40 who had a stroke to learn what factors might lead to dementia or memory problems later. Researchers looked at medical history, brain scans, and daily living skills. The goal was to identify risks and protective factors, not to test a tre…

This study looked at whether a program called Patient Priorities Care can work in regular doctor visits for people with dementia or mild cognitive impairment. 178 participants received a packet before their appointment and could talk with a trained helper about their personal car…

This study tested a way to reduce unnecessary medications for people with dementia. Researchers compared a personalized care approach to usual care in 45 patients and their caregivers. The goal was to see if focusing on what matters most to the patient leads to safer medication c…

This study tested a program to help nursing home staff better discuss and record care preferences for people with Alzheimer's or related dementias. The goal was to reduce unwanted hospital visits by making sure patients' wishes are known and followed. Over 47,000 residents in nur…

This study tested a new program that screens older adults (60+) for memory and thinking problems after they leave the intensive care unit (ICU). The goal was to see if the screening is practical and helps connect people to support. About 109 participants took part, and the progra…

This study tested a social robot that leads activities like trivia and reminders for people with Alzheimer's or other dementias living in assisted care. 26 residents, family members, and staff took part to see if the robot helped with engagement and mood. The goal was to understa…

This study followed 169 elderly patients (over 60) with depression who were treated at specialized clinics in Norway. Researchers checked on them after one and three years to see how their depression progressed and whether they developed dementia. The goal was to better understan…

This completed study surveyed 219 family caregivers of people with dementia to understand how swallowing difficulties (dysphagia) impact caregiver burden. Caregivers completed a one-time online questionnaire about their loved one's swallowing, their own stress, and support. The g…

This study tested whether specially designed tablet games, called VibrantMinds, can measure and improve cognitive skills in older adults with mild cognitive impairment or dementia. 26 participants aged 65 and older played the games, and researchers tracked changes in thinking, mo…

This study looked at over 11,000 adults in Trøndelag, Norway to find out how many people have dementia and how many of those cases are not diagnosed. Researchers used standard tests to measure memory and thinking skills. The goal is to better understand who gets dementia and why …

This study tested whether a single virtual reality (VR) session, where caregivers experience what it's like to have dementia, could improve their empathy and attitudes. 227 caregivers of people with dementia took part. The results showed that the VR group had better empathy and a…

This study looked at how common dementia and memory problems are in older Mexican Americans compared to non-Hispanic whites. Researchers tracked thinking skills over time and checked what help caregivers need. The goal was to find better ways to support patients and families.

This study looked at whether specially trained senior volunteers can help families caring for someone with Alzheimer's or dementia. The goal was to connect families with community services and improve their interactions with doctors. 44 people with dementia and their caregivers t…

This pilot study tested an online educational program called the Brain Health Support Program (BHSP) designed to teach people about dementia and how to lower their risk through lifestyle changes like diet, exercise, and social connection. Twenty adults with mild memory concerns o…

This study looked at whether a learning technique called 'retrieval practice' can help family caregivers better remember information about Alzheimer's disease and related dementias. 65 informal caregivers in the US took online tests to see if this method improves their knowledge …

This study tested whether a virtual reality (VR) program could help older adults with mild cognitive impairment learn more about dementia and improve their health skills. 139 participants aged 65 and older were split into two groups: one used a VR education module, and the other …

This study tested a computer system that helps doctors identify older patients at risk for memory problems or dementia. Over 3,200 adults aged 65 and older took part. The goal was to see if the tool could lead to earlier diagnosis and better care planning, without requiring extra…

This study looked at whether a special learning technique called 'retrieval practice' (like taking practice tests) helps dementia caregivers remember important information about symptoms and treatments. 73 caregivers took part in online sessions. The goal was to see if this metho…

This study tested a structured oral health care program for 64 older adults with dementia at a day care center. Over 4 weeks, researchers checked if the program improved oral hygiene and mouth function. The goal was to see if a simple, regular routine could make a difference for …

This study followed over 18,000 Taiwanese adults to see if a vegetarian diet is linked to a lower risk of chronic diseases like dementia, depression, heart disease, stroke, gout, cataracts, gallstones, and urinary tract infections. Researchers used health insurance records to tra…

This study adapted a program called BECOME to help people with dementia or mild cognitive impairment and their caregivers manage chronic diseases like diabetes and high blood pressure, along with mental health issues like depression and anxiety. The researchers worked with a smal…

This study looked at whether cochlear implants, devices that help people hear, can also improve thinking and memory in adults aged 65 and older with hearing loss. Researchers gave participants memory and attention tests before getting the implant, then again at 6 months, 1 year, …

This study aimed to find very early signs of Alzheimer's disease in the brain before memory problems start. Researchers used brain scans to measure changes in areas like the hippocampus in 304 retired farmers aged 65 and older who had no reported thinking difficulties. The goal w…

This study tested a digital tool that scans electronic health records to find older adults who may have undetected memory problems or early Alzheimer's disease. Over 3,400 patients aged 65 and older from primary care clinics took part. The goal was to see if the tool could help i…

This study looked at whether emergency department pharmacists can safely identify and recommend stopping certain medications that may be harmful for people with dementia or mild cognitive impairment. Researchers worked with 300 adults to see if pharmacists could communicate these…

This study checks if a questionnaire called SCREEN can correctly find older adults (55+) who are at risk of malnutrition, especially those with mild memory loss or dementia. Researchers will ask about 600 seniors and their caregivers to fill out the form and compare results with …

This study tested a new program to help caregivers and people with dementia who receive medical care at home. Researchers worked with two home-care practices to see if the program was practical and well-received. The goal was to improve quality of life and reduce caregiver stress…

This study collected blood samples from over 2,200 people with dementia (like Alzheimer's) and healthy volunteers to find genes linked to these brain diseases. Researchers compared DNA from patients and their families to discover new genetic causes and risk factors. The goal is t…

This study looked at how common mild memory problems are in adults aged 50-65 in Kerala, India, and tested whether a multi-step program to prevent further memory decline is practical. Researchers enrolled 481 participants, measured their thinking skills, and then offered a one-mo…

This study tested a training program for home care workers who care for people with dementia. The program used realistic scenarios to help workers improve their empathy, preparedness, and competence. 70 full-time home care workers took part, and the study measured changes in thei…

This study analyzed health records from nearly 1 million Canadian adults to see how the COVID-19 pandemic affected primary care for chronic conditions like diabetes, heart failure, and depression. Researchers looked at changes in doctor visits, tests, and treatments before and du…

This study looked at whether a nutrition program could work for people with dementia who receive home care. Researchers worked with 139 participants, including people with dementia, their family carers, and home care staff, to see if the program was practical and well-received. T…

This study tested two ways of training long-term care workers in Minnesota to provide better care for LGBTQ+ residents with Alzheimer's or dementia. Over 760 staff members took part in either in-person or online training. The goal was to see if the training improved staff knowled…

This study tested a program called Home Alone for older adults with memory problems who live by themselves. The goal was to see if the program was helpful and acceptable. Participants worked with a coach in weekly sessions to stay active, engaged, and safe at home. The study invo…

This study tested a new approach to help older Latinos with dementia get better care. Researchers trained primary care doctors in Kansas City to improve their skills in detecting dementia and referring patients to a Health Navigator. The Navigator then provided support and connec…

This study followed 404 older adults who had surgery for a broken hip to see how long they lived over the next 10 years. Researchers checked whether early signs of Alzheimer's disease in the brain (measured in spinal fluid) or memory problems before the fracture were linked to hi…

This study examined health records of over 68,000 adults aged 40 and older to see if those who develop lasting nerve pain after shingles have a higher chance of getting dementia later. Researchers compared people with and without this nerve pain, matching them by other health fac…

This study looked at whether self-compassion (being kind to yourself) helps older adults feel better about life after a dementia diagnosis. Researchers also checked if feeling threatened by dementia affects this link. 23 older adults with a recent dementia diagnosis took part in …

This study involved over 6,000 Medicare patients with mild cognitive impairment or dementia. Researchers wanted to see if a special brain scan (amyloid PET) helps doctors make better treatment decisions and improves patient outcomes. The study focused on including people from div…

This study looked at whether measuring the electrical activity of the skin can warn caregivers that a person with dementia is about to become agitated or aggressive. 21 patients from a dementia unit took part. The goal was to see if these skin signals appear early enough to allow…

This study aimed to create a communication tool to help people with Alzheimer's or dementia and their caregivers discuss and plan for future medical care. Researchers worked with 38 participants to see if the tool improved their readiness to make advance care plans. The goal was …

This study tested a special education course called Caregiving While Black-LIVE for Black caregivers of people with dementia. The goal was to help them feel more confident and supported when dealing with healthcare providers. Forty caregivers took part, and researchers measured t…

This study tested a simple idea: sending gentle reminders (nudges) to doctors and caregivers to help reduce or stop certain high-risk medications in people with dementia. Researchers worked with 250 patients aged 65 and older to see if this approach was practical and could be mea…

This study tested a program to help people with dementia in assisted living document their medical care wishes, like whether to be resuscitated or hospitalized. Over 2,300 residents took part, with some receiving the planning program and others usual care. The goal was to see if …

This study tested whether a nurse-led walking and sit-to-stand program is practical and liked by older adults with cognitive issues like dementia in transitional care. Six participants took part to see if the program could improve strength, mobility, and quality of life. The main…

This study looked at whether restoring proper chewing function can improve brain health and delay cognitive decline. Researchers worked with 150 adults who needed dental treatment or had misaligned teeth. They used brain scans and thinking tests to see if fixing dental problems h…

This completed study tested whether an AI platform can detect mild cognitive impairment and dementia by analyzing speech. Researchers compared language patterns from 196 older adults (55+) with standard cognitive tests. The goal was to see if speech changes can serve as a screeni…

This study tested a new computer system that uses artificial intelligence to help doctors better diagnose and treat complex brain disorders like dementia, epilepsy, and sleep problems. Researchers collected information from 635 people, including healthy volunteers, to see if the …

This study tested whether a fun, interactive program using music and dance could help parents and children learn more about Alzheimer's disease. Over 2,200 families from New York City schools took part. Researchers measured their knowledge before and after the program, and again …

This study reviewed medical records of 683 older adults with dementia to see if their antiplatelet medications (like aspirin) were prescribed appropriately according to guidelines. Researchers looked at different types of dementia and compared real-world prescribing to recommende…