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Cure My Disease

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Chewing your way to a healthier brain?

NCT ID NCT02986386

Disease control Sponsor: Universidad de Granada Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether restoring proper chewing function through dental implants or braces could improve cognitive health in adults. Researchers enrolled 150 people with missing teeth or misaligned bites. They measured changes in brain activity, thinking skills, and mood. The goal was to see if better chewing might help delay dementia.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dental implants or orthodontic treatment
What this could lead to
If it works, this could point toward a simple way to support brain health by improving chewing ability.
What could go wrong
This is a small, completed study with 150 participants. It only looks at short-term changes in brain activity and thinking, not whether it actually prevents dementia.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 150 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2016

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 75 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * For Dental occlusion restoration groups: Need of, at least, two molar teeth replacement in the same quadrant. * For Orthodontic treatment of malocclusion groups: Class I, II or III malocclusion. Exclusion Criteria: * Psychoactive drug. * Central nervous system depressor. * Patients not willing or not able to consent.

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Conditions

The condition(s) this trial relates to.

Bites and Stings dementia Malocclusion Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dementia Malocclusion

Contacts and locations

Locations

  • Facultad de Odontología

    Granada, Granada, 18071, Spain

More trials for these conditions

Other studies related to the condition(s) this trial covers.