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Vegetarian diet linked to lower risk of dementia, heart disease, and more in massive study

NCT ID NCT03470584

Knowledge-focused Sponsor: Dalin Tzu Chi General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This completed study followed over 18,000 Taiwanese Buddhists to see if a vegetarian diet is linked to a lower risk of chronic diseases like dementia, depression, heart disease, stroke, gout, cataracts, gallstones, and urinary tract infections. Researchers compared health records of vegetarians and non-vegetarians over time. The goal is to understand how diet may influence long-term health.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Vegetarian diet
What this could lead to
If it shows clear links, this could help people understand how a vegetarian diet might lower the risk of several chronic diseases.
What could go wrong
This is an observational study, not a controlled trial, so it can only show associations, not cause and effect. Other lifestyle factors may influence the results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

18,064 people

The number who actually took part.

Started

Mar 2005

Finished

Dec 2014

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Participants in the Tzu Chi Vegetarian Study were all certified volunteers of the Buddhist Tzu Chi Foundation. Participants of the Tzu Chi Health Study were the ones who came to the Dalin Tzu Chi Hospital for health examination and agree to join the cohort study (77% were certified Tzu Chi volunteers). About 1/3 of both cohorts were vegetarians at enrollment.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Participants who consent to be followed. Exclusion Criteria: * Participants with inaccurate ID which make linkage to NHIRD impossible. * Participants already with study outcome (disease) prior to enrollment in the study. * Participants with missing covariates

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Conditions

The condition(s) this trial relates to.

cardiovascular disorder cataract dementia Depression depressive disorder gallstones gout stroke disorder urinary tract infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cardiovascular diseases Cataract Dementia Depression Gallstone Gout Stroke Urinary tract infections

Contacts and locations

Locations

  • Dalin Tzu Chi Hospital

    Chiayi City, Taiwan

More trials for these conditions

Other studies related to the condition(s) this trial covers.