URINARY TRACT INFECTIONS

This study tests a new vaccine designed to prevent urinary tract infections (UTIs) caused by E. coli bacteria. Researchers will check safety and immune response in 448 adults aged 18-64, and then see if it works in women of the same age. Participants receive either the vaccine or…

This study tests whether giving oral antibiotics instead of IV antibiotics is just as safe and effective for patients with common infections like pneumonia, urinary tract infections, and cellulitis. About 4,000 adults in Danish emergency rooms will be randomly assigned to start o…

This study tests a new treatment called LBP-EC01, made from viruses that attack bacteria, for urinary tract infections (UTIs) that don't respond to standard antibiotics. About 318 adults with a history of UTIs and a current infection caused by drug-resistant E. coli will receive …

This study tests two methods to prevent repeat bladder infections in women over 40 who have gone through menopause. One group takes a nightly antibiotic for 6 months, while the other uses a vaginal tablet containing good bacteria and a low-dose hormone. The goal is to see which a…

This study tests whether a simple technique called "double voiding" (urinating twice in a row) can reduce urinary tract infections (UTIs) in kidney transplant recipients. UTIs are common after transplant and can lead to serious complications. The study will follow 438 adults at o…

This study compares a new DNA-based test (PCR) to the standard urine culture for diagnosing urinary tract infections (UTIs) in adults. About 136 people with UTI symptoms will be randomly assigned to one of the two tests. Researchers will track how quickly treatment starts, how sy…

This study looks at whether a DNA-based urine test (called Next Generation Sequencing) can find bacteria that standard urine cultures miss. It involves 100 women with UTI symptoms but low bacteria counts on the usual test. The goal is to see if the DNA test leads to better treatm…

This study looks at whether a single injection of the antibiotic amikacin can effectively treat uncomplicated bladder infections in women visiting the emergency department. Instead of taking pills for several days, participants receive one shot into a muscle or vein. The goal is …

This study is testing whether a 21-day spa program—including mineral water baths, exercise, and diet—can improve kidney function and reduce symptoms in 150 adults aged 40-70 with chronic kidney or urinary tract diseases. Participants receive standard spa care at a resort in the C…

This study tests a prediction model to help doctors decide if antibiotics are really needed for urinary tract infections (UTIs) in the emergency room. About 47 women with UTIs will be enrolled. The goal is to reduce unnecessary antibiotic use and fight antibiotic resistance.

This study looks at whether scheduling automatic follow-up appointments after a child leaves the hospital is better than only seeing a doctor when needed. About 2,674 children hospitalized for pneumonia, urinary tract infections, skin infections, or stomach bugs will take part. T…

This early-stage study is testing a new drug called JKN2501 in 66 healthy adults in China. The goal is to see if the drug is safe and how the body processes it, not to treat any disease. Participants will receive either the drug or a placebo by IV, and researchers will monitor fo…