Universitaire Ziekenhuizen Ku Leuven

This study tests different biomaterials to repair bone damage around teeth caused by gum disease. 30 adults who still have deep gum pockets after non-surgical treatment will receive a minor surgical procedure. During surgery, the bone defect is cleaned and then filled with one of…

This study tests whether a program of nutrition, physical activity, and mindfulness can help women with twin pregnancies carry their babies longer, reducing preterm birth. Researchers will first test the program in 81 women to see if it's practical, then expand to a larger study.…

This study compares a new imaging tracer, [18F]-AlF-FAPI-74, with the standard [18F]-FDG in PET/CT scans for three inflammatory conditions: fever of unknown origin, IgG4-related disease, and axial spondyloarthritis. Researchers aim to see if the new tracer is as good or better at…

This study compares two types of minimally invasive surgery—robotic and laparoscopic—for people with inflammatory bowel disease (IBD) who need colorectal surgery. The goal is to see which method causes fewer complications, less pain, and a quicker recovery. About 110 adults will …

This study looks at whether adding tongue scraping to standard gum treatment can improve bad breath in people with periodontitis (gum disease). About 39 adults with gum disease and bad breath will receive standard gum cleaning and oral hygiene instructions, with half also using a…

This study aims to understand why some people get very sick from COVID-19 while others do not. Researchers will analyze blood samples and genetic information from 100 hospitalized adults with confirmed COVID-19. The goal is to identify immune system patterns and genetic factors t…

This study aims to create reliable methods for measuring balance and trunk strength in adults with spinal deformity. Researchers will compare 30 patients with spinal deformity to healthy volunteers to build a first-of-its-kind database. The goal is to better understand how spinal…

This study collects images and videos of large colon polyps taken during standard colonoscopy. The goal is to use these images to train an artificial intelligence (AI) system to predict whether a polyp has cancer invading deeper layers. About 5,000 adults undergoing colonoscopy w…

This study looks at how the bones in the shoulder joint touch each other in people with shoulder arthritis, both before and after shoulder replacement surgery. The goal is to find out why some shoulder implants loosen over time. Researchers will compare patients with arthritis to…

This study looks at a hip condition called FAI, where bone shape causes pain during movement. Researchers will compare 99 men (21-35 years old) with and without symptoms to see how spine and hip motion differ. The goal is to better understand why some people with the bone shape f…

This study follows 30 children with cow's milk allergy who did not become tolerant after a previous treatment. Researchers will track how many naturally develop tolerance over time and note any reactions to milk. The goal is to better understand the allergy's natural course, not …

This study looks at how adults with spinal deformities (like abnormal curves) keep their balance while standing and walking. Researchers will use motion analysis, muscle activity tests, and quality-of-life surveys to better understand these movements. The goal is to improve futur…

This study looks at how people who had surgery for bone or soft tissue sarcoma in their leg move and feel in daily life. Researchers will measure physical function, quality of life, and activity levels in 60 adults who are at least one year past surgery. The goal is to understand…

This study follows 50 adults with hip prosthetic joint infections treated at University Hospitals Leuven. Researchers will collect data on infection clearance, treatment choices, and complications to improve future care and inform patients about success rates. No new treatments a…

This study looks at how muscles change as children with spastic cerebral palsy grow. Researchers will use 3D ultrasound to measure muscle size, length, and quality over time. The goal is to better understand these changes and how they relate to brain injuries and treatments. Abou…

This study aims to understand how different forms of vitamin D work in the body, especially the 'free' form that cells can use directly. Researchers will compare healthy people, pregnant women, and patients with hormone or kidney disorders to see if measuring free vitamin D gives…

This study looks at how the skin on the feet reacts to natural compounds like cinnamon, mustard, and chili. Researchers will measure blood flow and any pain in 20 healthy adults. The goal is to better understand nerve function, which could help future research on diabetic nerve d…