The University Of Hong Kong

This is a small pilot study to see if a chatbot powered by artificial intelligence (AI) is a practical and acceptable tool for helping people with a specific type of fatty liver disease (MetALD) drink less alcohol. The study will recruit 50 adults in Hong Kong who have the diseas…

This study is testing whether using a Fitbit, either alone or combined with a health coaching program, can help adults with central obesity move more and improve their heart health markers. Over 130 participants aged 40+ will be randomly assigned to use the device, use the device…

This pilot study is testing a new strategy for patients with liver cancer that cannot be surgically removed. Researchers will combine immunotherapy (which uses the body's immune system) with highly focused radiation to try to shrink tumors. The goal is to make the cancer small en…

This study is testing a 16-week education and support program designed for heart failure patients and their primary caregivers. The program aims to teach them how to work together to better manage symptoms, diet, and medication after a hospital stay. Researchers want to see if th…

This study is testing whether regular exercise, with or without telehealth support, can help smokers and former smokers who have early signs of reduced lung function. Researchers want to see if exercise can improve how far participants can walk and potentially slow the progressio…

This study is testing if a medication called vericiguat can improve blood flow in the smallest heart vessels and reduce chest pain in people who have pain but no major artery blockages. It will involve 94 adults with this specific condition, known as coronary microvascular dysfun…

This study is testing whether personalized oral hygiene advice from an artificial intelligence (AI) system can help people with prediabetes manage their gum health and blood sugar levels as well as advice from a human dentist. Researchers will compare the two methods over nine mo…

This study is testing whether a mobile phone app can help people who have survived a type of stroke (brain bleed) better control their high blood pressure. 140 stroke survivors will either use the app to track their blood pressure daily and get support calls, or receive their usu…

This study is testing whether a new surgical tool can help prevent a common and serious complication after thyroid removal surgery. The tool uses a special light to help the surgeon see and protect tiny glands near the thyroid. Researchers will compare surgery using this new prob…

This study is testing different exercise programs to see which ones best help older adults stay healthy and independent. Researchers will assign nearly 2,000 participants over age 60 to various exercise groups or a no-exercise comparison group. The programs include options like f…

This study aims to see if using artificial intelligence (AI) during a colonoscopy helps prevent advanced colon growths from appearing in future check-ups. It follows 404 people who previously had either a standard colonoscopy or one assisted by AI. Researchers will compare how ma…

This study is testing whether a personalized 12-week lifestyle coaching program can help reverse metabolic syndrome—a cluster of conditions like high blood pressure and high blood sugar that increase heart disease risk. Researchers will compare this intensive program to simple on…

This study is evaluating a community program designed to help isolated older adults in Hong Kong. Researchers will measure how the program affects participants' physical ability, memory, mood, loneliness, and overall quality of life. The goal is to see if connecting these 'hard-t…

This study is testing whether a 14-week home exercise program using elastic resistance bands can help improve muscle loss (sarcopenia) in older adults with heart failure. Researchers want to see if this simple training can strengthen muscles, improve physical function, and ease s…

This study is testing a 14-week healthy aging program to see if it helps older adults feel better and stay more active. Researchers will compare 1,000 participants who either receive the program or do not. The goal is to see if the program improves quality of life, strength, bala…

This study is testing if a drug called tranexamic acid (TXA) can help control brain damage after a specific type of stroke called an intracerebral hemorrhage (brain bleed). Researchers are trying a new, more precise method to select which patients might benefit most, based on whe…

This small pilot study is testing whether stimulating the spinal cord in two places—at the injury site and in the lower back—can help people with long-term, severe spinal cord injuries regain leg movement and control. Five participants will have a stimulator implanted and undergo…

This study is testing a 12-week program called ENACT that combines hearing exercises with memory training. It aims to help older adults who have both mild memory problems and hearing loss. Researchers want to see if this combined approach can improve communication, thinking skill…

This study tests a personalized plan to control high blood pressure after a severe type of stroke caused by bleeding in the brain. Researchers will use a special score to identify patients who might benefit most from starting three blood pressure medications together right away. …

This study is testing whether a computer AI system helps doctors find more abnormal growths in the stomach during a routine camera test (endoscopy). 1000 patients will have two back-to-back exams: one with the AI's help and one without, in a random order. The goal is to see if th…

This study is testing a new artificial intelligence (AI) tool designed to help surgeons plan and perform a specific type of complex jaw reconstruction surgery. The AI analyzes medical scans to automatically map the tiny blood vessels that supply skin, which are critical for the s…

This study aims to create a simple, rapid test to detect poisoning from toxic herbs used in traditional Chinese medicine. Researchers will test the new device using urine samples from 90 people, including those who have been poisoned, those using the herbs as medicine, and health…

This study is testing whether personalized text messages and online educational games can help teenagers in Hong Kong reduce their alcohol use and avoid binge drinking. Researchers will enroll 100 teens aged 12-18 who have drunk alcohol in the past year. Half will receive the tex…

This study is testing whether experiencing a feeling of awe can make adults more willing to take actions that prevent the spread of infectious diseases. Researchers are recruiting about 450 adults from Hong Kong, Singapore, and major cities in China. Participants will be randomly…

This study is testing a 20-week home exercise program designed for older adults who are at risk of losing strength and mobility after a hospital stay. Researchers want to see if a personalized, strength-based exercise routine done at home can help improve physical function and qu…

This study is testing whether a specific type of music therapy, where students write songs, can help reduce feelings of depression, anxiety, and stress while improving social connections. Researchers will compare songwriting sessions to simple music listening and discussion in 20…

This study tests whether showing children real-time ultrasound images of their tongue movements helps them learn to pronounce sounds correctly. Researchers are comparing immediate ultrasound-guided therapy to standard care in 60 children with speech sound disorders. The goal is t…

This study is testing whether automated, personalized text messages can help people with mild cognitive impairment manage their mood and behavior symptoms. The messages deliver Acceptance and Commitment Therapy, a type of psychological support, and are sent based on each particip…

This study is testing whether a specific type of talk therapy, called narrative therapy, can help young people in Hong Kong who are experiencing moderate mental distress. About 770 participants, aged 12 to 24, will be assigned to either receive six therapy sessions right away or …

This study is testing whether a mobile app with nurse support can help family caregivers of cancer patients who struggle with insomnia. 208 caregivers will be randomly assigned to either use a 6-week cognitive behavioral therapy program on a WeChat app or receive standard sleep h…

This study is testing whether a smartphone chatbot called Digi-Coach can help reduce physical and emotional distress for people undergoing radiation treatment for head and neck cancer. Researchers will compare patients using the AI chatbot alongside regular nursing care to those …

This study is testing whether a type of talk therapy for insomnia (CBT-I) can help reduce impulsive actions and risky decision-making in young people with sleep problems. Researchers will compare the therapy to a basic sleep education program in about 124 participants aged 12-24.…

This study is testing a new group support program designed to help families caring for children with special needs. The program aims to reduce parenting stress and improve overall wellbeing for both caregivers and their children. Researchers will see if the group sessions are pra…

This study is testing a special exercise program called 'sport stacking' (quickly stacking and unstacking cups) for people with mild dementia and the family members who care for them. The goal is to see if doing these activities together can help improve the person's thinking ski…

This study is testing whether a special type of story can make dental visits easier for young autistic children. Researchers are using illustrated 'social stories' that explain what happens at the dentist step-by-step to help kids know what to expect. The trial will see if childr…

This study is testing whether weekly mindfulness sessions, attended together by a person with Parkinson's and their main caregiver, can help reduce stress and improve their relationship. Researchers will enroll 100 pairs in Hong Kong, with half receiving the mindfulness program a…

This study is testing whether a 6-week online group program on WeChat can help older adults with heart failure feel less socially isolated and improve their self-care. Researchers will compare the chat-based program, which includes video meetings and daily check-ins, to giving pa…

This study is testing a new 8-week program that combines mindfulness training with personalized exercise coaching for people with chronic obstructive pulmonary disease (COPD). The goal is to see if this hybrid approach can help reduce stress, improve breathing, and increase physi…

This study is testing whether a gentle, non-invasive brain stimulation technique can help improve mood and emotional regulation in young adults experiencing mild depressive symptoms. Researchers will compare real stimulation to a placebo-like sham treatment to see if it reduces d…

This study is testing a new support program for family members caring for someone with dementia. The program aims to help caregivers manage their stress, difficult emotions, and feelings of depression. Researchers will compare this new program to standard support to see if it wor…

This study is testing whether a smartphone app that teaches parents behavioral sleep techniques can help children with autism who have trouble sleeping. It will also see if the app improves parents' own sleep, stress, and mental health. About 195 families will be randomly assigne…

This study is testing whether a special game can help adults who have experienced major life stress feel better emotionally and build mental resilience. Researchers will compare 50 adults playing the game for 10 days against a group waiting to play, measuring their mood and stres…

This study aims to find the best dose of a long-acting numbing medicine (liposomal bupivacaine) given as a nerve block to control pain after knee replacement surgery. Researchers will compare how well different doses reduce pain and the need for opioid painkillers in 177 adults u…

This study is testing an online self-management program designed to help Chinese cancer survivors who have a moderate fear of their cancer returning. The program, called eConquerFear-HK, teaches coping strategies and is being compared to a standard control activity. Researchers w…

This study aims to understand why getting a flu shot every year might make it less effective for some people. Researchers will follow 600 healthy adults in Hong Kong, giving them different combinations of flu shots and nasal spray vaccines over two years to see how their immune s…

This study aims to see if using a visual life history calendar helps people in Hong Kong remember their mental health history more accurately. Researchers will compare the standard mental health interview with and without the calendar tool. The goal is to improve how we measure h…