Bacterial infectious disease
MONDO:0005113An acute infectious disorder that is caused by gram positive or gram negative bacteria; representative examples include pneumococcal, streptococcal, salmonella, and meningeal infections.
Also known as: Bacteria caused disease or disorder, Bacteria disease or disorder, Bacteria infectious disease, bacterial disease, bacterial disorder, bacterial infection, bacterial infectious disease, infection, bacterial
2079 clinical trials for this condition and its sub-types, 96 tagged with Bacterial infectious disease itself.
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Sub-types of Bacterial infectious disease
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Primary bacterial infectious disease 0 trials · 593 incl. sub-types
37 sub-types
- Tuberculosis 218 trials · 299 incl. sub-types Sub-types →
- Syphilis 47 trials · 56 incl. sub-types Sub-types →
- Gonorrhea 49 trials Sub-types →
- Tetanus 44 trials Sub-types →
- Lyme disease 31 trials
- Diphtheria 27 trials Sub-types →
- Mycobacterium avium complex disease 22 trials
- Anthrax infection 17 trials · 20 incl. sub-types Sub-types →
- Salmonellosis 5 trials · 19 incl. sub-types Sub-types →
- Cholera 16 trials
- Shigellosis 14 trials
- Leprosy 11 trials · 12 incl. sub-types Sub-types →
- Leptospirosis 9 trials Sub-types →
- Botulism 5 trials Sub-types →
- Listeriosis 4 trials Sub-types →
- Plague 2 trials · 4 incl. sub-types Sub-types →
- Buruli ulcer disease 3 trials
- Q fever 3 trials
- Campylobacteriosis 3 trials Sub-types →
- Melioidosis 3 trials
- Brucellosis 2 trials Sub-types →
- Legionellosis 1 trial · 2 incl. sub-types Sub-types →
- Relapsing fever 2 trials Sub-types →
- Bartonellosis 0 trials · 1 incl. sub-types Sub-types →
- Ehrlichiosis 1 trial Sub-types →
- Granuloma inguinale 0 trials · 1 incl. sub-types Sub-types →
- Ornithosis 1 trial
- Pinta disease 1 trial
- Borrelia miyamotoi disease 0 trials
- Chancroid 0 trials
- Glanders 0 trials
- Rhinoscleroma 0 trials
- Sennetsu fever 0 trials
- Spirillary rat-bite fever 0 trials
- Staphyloenterotoxemia 0 trials
- Streptobacillary rat-bite fever 0 trials
- Tularemia 0 trials Sub-types →
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Mycobacterial infectious disease 23 trials · 361 incl. sub-types
7 sub-types
- Tuberculosis 218 trials · 299 incl. sub-types Sub-types →
- Pulmonary non-tuberculous mycobacterial infection 48 trials
- Mycobacterium avium complex disease 22 trials
- Leprosy 11 trials · 12 incl. sub-types Sub-types →
- Buruli ulcer disease 3 trials
- Mycobacterium xenopi infection 2 trials
- Aquarium granuloma 0 trials
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Gram-negative bacterial infections 33 trials · 301 incl. sub-types
15 sub-types
- Helicobacter pylori infectious disease 115 trials
- Treponema infectious disease 7 trials · 58 incl. sub-types Sub-types →
- Chlamydiaceae infections 1 trial · 55 incl. sub-types Sub-types →
- Bordetellosis 0 trials · 39 incl. sub-types Sub-types →
- Moraxellaceae infectious disease 0 trials · 8 incl. sub-types Sub-types →
- Pneumonia caused by gram negative bacteria 5 trials · 7 incl. sub-types Sub-types →
- Rickettsiaceae infectious disease 0 trials · 4 incl. sub-types Sub-types →
- Burkholderia infectious disease 0 trials · 3 incl. sub-types Sub-types →
- Anaplasmataceae infectious disease 0 trials · 2 incl. sub-types Sub-types →
- Bartonellaceae infectious disease 0 trials · 1 incl. sub-types Sub-types →
- Bacteroidaceae infectious disease 0 trials Sub-types →
- Desulfovibrionaceae infectious disease 0 trials
- Fusobacteriaceae infectious disease 0 trials Sub-types →
- Bacterial meningitis caused by gram-negative bacteria 0 trials Sub-types →
- Streptobacillus infectious disease 0 trials Sub-types →
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Commensal bacterial infectious disease 0 trials · 273 incl. sub-types
6 sub-types
- Toxic shock syndrome 225 trials Sub-types →
- Chlamydia trachomatis infectious disease 37 trials · 48 incl. sub-types Sub-types →
- Lemierre syndrome 0 trials
- Actinomycosis 0 trials Sub-types →
- Gas gangrene 0 trials
- Staphylococcal scalded skin syndrome 0 trials
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Gram-positive bacterial infections 7 trials · 253 incl. sub-types
6 sub-types
- Streptococcal infection 19 trials · 132 incl. sub-types Sub-types →
- Clostridium infectious disease 48 trials · 97 incl. sub-types Sub-types →
- Bacillaceae infectious disease 1 trial · 20 incl. sub-types Sub-types →
- Actinomycetales infectious disease 1 trial Sub-types →
- Erysipelothrix infectious disease 0 trials Sub-types →
- Infection caused by Bifidobacterium 0 trials
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Pulpitis 191 trials
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Bacterial sexually transmitted disease 8 trials · 114 incl. sub-types
5 sub-types
- Treponema infectious disease 7 trials · 58 incl. sub-types Sub-types →
- Chlamydia infectious disease 34 trials · 55 incl. sub-types Sub-types →
- Gonorrhea 49 trials Sub-types →
- Granuloma inguinale 0 trials · 1 incl. sub-types Sub-types →
- Chancroid 0 trials
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Bacterial infectious disease with sepsis 78 trials · 113 incl. sub-types
5 sub-types
- Neonatal sepsis 35 trials
- Lemierre syndrome 0 trials
- Pasteurella hemorrhagic septicemia 0 trials
- Gas gangrene 0 trials
- Meningococcemia 0 trials
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Anaerobic bacteria infectious disease 2 trials · 100 incl. sub-types
10 sub-types
- Clostridium infectious disease 48 trials · 97 incl. sub-types Sub-types →
- Actinomycetales infectious disease 1 trial Sub-types →
- Bacteroides infectious disease 0 trials
- Fusobacterium infectious disease 0 trials
- Peptostreptococcus infectious disease 0 trials
- Anaerobic balanitis 0 trials
- Anaerobic cellulitis 0 trials
- Anaerobic meningitis 0 trials
- Anaerobic pneumonia 0 trials
- Infection caused by Bifidobacterium 0 trials
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Spirochaetales infections 1 trial · 99 incl. sub-types
4 sub-types
- Treponema infectious disease 7 trials · 58 incl. sub-types Sub-types →
- Lyme disease 31 trials
- Leptospirosis 9 trials Sub-types →
- Borrelia infectious disease 6 trials · 7 incl. sub-types Sub-types →
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Bacterial arthritis 24 trials · 94 incl. sub-types
6 sub-types
- Periprosthetic joint infection 76 trials
- Escherichia coli discitis 0 trials
- Gonococcal infection of joint 0 trials Sub-types →
- Salmonella discitis 0 trials
- Staphylococcus discitis 0 trials
- Streptococcus pneumoniae discitis 0 trials
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Staphylococcal infection 41 trials · 84 incl. sub-types
4 sub-types
- Staphylococcus aureus infection 37 trials · 69 incl. sub-types Sub-types →
- Staphylococcal pneumonia 1 trial Sub-types →
- Staphylococcal toxemia 0 trials · 1 incl. sub-types Sub-types →
- Staphyloenterotoxemia 0 trials
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Bacterial urinary tract infection 55 trials · 81 incl. sub-types
8 sub-types
- Pyelonephritis 8 trials · 21 incl. sub-types Sub-types →
- Acute cystitis 7 trials Sub-types →
- Urethritis 5 trials · 6 incl. sub-types Sub-types →
- Gonococcal cystitis 0 trials Sub-types →
- Neonatal urinary tract infectious disease 0 trials
- Renal tuberculosis 0 trials
- Ureter tuberculosis 0 trials
- Urinary bladder tuberculosis 0 trials
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Clostridium difficile colitis 69 trials
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Bacterial pneumonia 28 trials · 65 incl. sub-types
8 sub-types
- Streptococcal pneumonia 16 trials
- Mycoplasma pneumoniae pneumonia 9 trials
- Klebsiella pneumonia 7 trials
- Pneumonia caused by gram negative bacteria 5 trials · 7 incl. sub-types Sub-types →
- Pneumonia caused by pseudomonas aeruginosa infection 3 trials
- Legionnaires' disease 2 trials
- Staphylococcal pneumonia 1 trial Sub-types →
- Anaerobic pneumonia 0 trials
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Skin disease caused by bacterial infection 13 trials · 57 incl. sub-types
17 sub-types
- Cellulitis 29 trials · 31 incl. sub-types Sub-types →
- Hordeolum 1 trial · 7 incl. sub-types Sub-types →
- Impetigo 5 trials Sub-types →
- Cutaneous anthrax 2 trials
- Erysipelas 1 trial
- Pinta disease 1 trial
- Aquarium granuloma 0 trials
- Bacillary angiomatosis 0 trials
- Bacterial exanthem 0 trials
- Bullous impetigo 0 trials
- Cutaneous diphtheria 0 trials
- Cutaneous syphilis 0 trials Sub-types →
- Cutaneous tuberculosis 0 trials Sub-types →
- Gas gangrene 0 trials
- Gonococcal keratitis 0 trials
- Staphylococcal scalded skin syndrome 0 trials
- Sycosis barbae 0 trials
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Meningococcal infection 47 trials · 55 incl. sub-types
2 sub-types
- Meningococcal meningitis 18 trials
- Meningococcemia 0 trials
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Bifidobacteriales infectious disease 0 trials · 44 incl. sub-types
2 sub-types
- Bacterial vaginosis 44 trials
- Infection caused by Bifidobacterium 0 trials
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Bacterial meningitis 12 trials · 37 incl. sub-types
8 sub-types
- Meningococcal meningitis 18 trials
- Meningeal tuberculosis 7 trials
- Haemophilus meningitis 1 trial
- Escherichia coli meningitis 0 trials
- Listeria meningitis 0 trials
- Anaerobic meningitis 0 trials
- Bacterial meningitis caused by gram-negative bacteria 0 trials Sub-types →
- Streptococcal meningitis 0 trials Sub-types →
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Pseudomonas infection 25 trials · 29 incl. sub-types
1 sub-type
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Escherichia coli infection 26 trials
1 sub-type
- Escherichia coli discitis 0 trials
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Vibrio infectious disease 0 trials · 16 incl. sub-types
2 sub-types
- Cholera 16 trials
- Vibrio vulnificus infectious disease 0 trials
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Bacterial endocarditis 15 trials
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Mycoplasmoides infection 7 trials · 15 incl. sub-types
2 sub-types
- Mycoplasma pneumoniae pneumonia 9 trials
- Mycoplasma encephalitis 0 trials
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Haemophilus infectious disease 14 trials
2 sub-types
- Haemophilus meningitis 1 trial
- Chancroid 0 trials
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Necrotizing soft tissue infection 13 trials
2 sub-types
- Necrotizing cellulitis 0 trials
- Necrotizing myositis 0 trials
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Empyema 10 trials · 11 incl. sub-types
2 sub-types
- Subdural empyema 1 trial
- Tuberculous empyema 0 trials
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Chorioamnionitis 10 trials
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Klebsiella infectious disease 5 trials · 9 incl. sub-types
3 sub-types
- Klebsiella pneumonia 7 trials
- Granuloma inguinale 0 trials · 1 incl. sub-types Sub-types →
- Rhinoscleroma 0 trials
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Rickettsiosis 2 trials · 7 incl. sub-types
3 sub-types
- Rickettsiaceae infectious disease 0 trials · 4 incl. sub-types Sub-types →
- Anaplasmataceae infectious disease 0 trials · 2 incl. sub-types Sub-types →
- Tick-borne relapsing fever 0 trials
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Tracheitis 2 trials · 7 incl. sub-types
1 sub-type
- Laryngotracheitis 1 trial · 5 incl. sub-types Sub-types →
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Peritonsillar abscess 4 trials
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Enterococcus infectious disease 1 trial · 4 incl. sub-types
1 sub-type
- Enterococcus faecalis infection 3 trials
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Yersinia infectious disease 0 trials · 4 incl. sub-types
3 sub-types
- Plague 2 trials · 4 incl. sub-types Sub-types →
- Yersinia enterocolitica infectious disease 0 trials
- Yersinia pseudotuberculosis infectious disease 0 trials Sub-types →
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Bacterial conjunctivitis 3 trials
3 sub-types
- Gonococcal conjunctivitis 0 trials Sub-types →
- Inclusion conjunctivitis 0 trials
- Pseudomembranous conjunctivitis 0 trials Sub-types →
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Bacterial hemorrhagic fever 0 trials · 3 incl. sub-types
1 sub-type
- Scrub typhus 3 trials
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Bacterial gastritis 2 trials
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Fournier gangrene 2 trials
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Septic peritonitis 2 trials
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Opportunistic bacterial infectious disease 0 trials · 1 incl. sub-types
2 sub-types
- Nocardiosis 1 trial
- Cepacia syndrome 0 trials
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Actinobacillus infectious disease 0 trials
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1 sub-type
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Pectobacterium carotovorum infection 0 trials
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Proteus infectious disease 0 trials
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Whipple disease 0 trials
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Bacterial myositis 0 trials
1 sub-type
- Pyomyositis 0 trials
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Botryomycosis 0 trials
2 sub-types
- Cutaneous botryomycosis 0 trials
- Visceral botryomycosis 0 trials
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Idiopathic severe pneumococcemia 0 trials
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Noma 0 trials
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Pasteurellosis 0 trials
1 sub-type
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Pneumonic pasteurellosis 0 trials
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Rat-bite fever 0 trials
2 sub-types
- Spirillary rat-bite fever 0 trials
- Streptobacillary rat-bite fever 0 trials
Most studied deeper sub-types
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New vaccine aims to shield against deadly meningitis strains
Vaccine Recruiting nowThis study tests a new vaccine designed to protect against four types of meningococcal bacteria that can cause serious infections like meningitis and sepsis. About 1,100 healthy adults aged 19 to 55 will receive a single dose to see how well it triggers the immune system and if i…
Phase 2/3 • Sponsor: EyeGene Inc. • Aim: Vaccine
Last updated Jun 27, 2026 08:00 UTC
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New hope for Kids' diarrhea: drug plus fluids tested
Disease control Recruiting nowThis study tests how the drug rifaximin (Xifaxan) works in children aged 6 to 11 with acute diarrhea likely caused by bacteria. Half the children get the drug plus oral rehydration therapy, the other half get rehydration alone. Researchers want to see if adding the drug helps dia…
Phase 4 • Sponsor: Bausch Health Americas, Inc. • Aim: Disease control
Last updated Aug 15, 2026 00:00 UTC
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Could a simple blood test curb antibiotic overuse in sick kids?
Disease control Recruiting nowThis trial tests whether using a blood marker called procalcitonin (PCT) to guide antibiotic decisions can safely shorten treatment duration in children with bacterial infections in intensive care. About 296 children will be randomly assigned to either PCT-guided care or standard…
Sponsor: University Hospital, Toulouse • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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New hope for blood cancer patients: drug aims to slash infection risk
Disease control Recruiting nowThis study tests whether a medicine called XEMBIFY, given every two weeks alongside standard care, can reduce serious bacterial infections in adults with certain blood cancers (chronic lymphocytic leukemia, multiple myeloma, or non-Hodgkin lymphoma) who also have low antibody lev…
Phase 3 • Sponsor: Grifols Therapeutics LLC • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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New drug CTX-187 takes aim at stubborn bacterial infections
Disease control Recruiting nowThis first-in-human trial tests an experimental drug called CTX-187 for safety and tolerability. It starts with healthy volunteers to assess single and multiple doses, then moves to patients with bronchiectasis who have a chronic Pseudomonas infection. The goal is to see if the d…
Phase 1 • Sponsor: Centauri Therapeutics Limited • Aim: Disease control
Last updated Jul 18, 2026 00:00 UTC
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Can smarter antibiotic choices curb superbugs in liver disease?
Disease control Recruiting nowThis trial tests whether using infection surveillance data to guide antibiotic selection can reduce antibiotic resistance in hospitalized cirrhosis patients with bacterial infections. About 198 adults with decompensated cirrhosis and a confirmed or suspected infection will be ran…
Phase 4 • Sponsor: Eva Bonfill • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Antibiotic shot under skin could replace IV drip for serious infections
Disease control Recruiting nowThis study is testing whether a powerful antibiotic called piperacillin/tazobactam can be given as a continuous shot under the skin instead of through an IV line. About 240 adults with serious bacterial infections will be randomly assigned to receive the drug either subcutaneousl…
Phase 2 • Sponsor: Azienda Sanitaria Universitaria Friuli Centrale • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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New antibiotic eye drops aim to cure pink eye faster
Disease control Recruiting nowThis phase 3 trial tests whether fusidic acid 1% eye drops can cure bacterial conjunctivitis (pink eye) better than a placebo. About 400 adults and children with confirmed bacterial infection will receive either the antibiotic or placebo drops for a short time. The study measures…
Phase 3 • Sponsor: Baxis Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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New drug AV-001 aims to help hospitalized pneumonia patients breathe easier
Disease control Recruiting nowThis study tests a new drug called AV-001 in 120 hospitalized adults with pneumonia who need extra oxygen. The drug is given daily for up to 28 days alongside standard care. The goal is to see if it is safe and helps patients recover faster from pneumonia caused by COVID-19 or ot…
Phase 2 • Sponsor: Vasomune Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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New trial aims to outsmart superbug in ICU patients
Disease control Recruiting nowThis study tests three different antibiotic combinations to treat a dangerous, drug-resistant bacteria called CRAB that causes infections in intensive care patients. Researchers will compare colistin combined with either fosfomycin, ampicillin/sulbactam, or eravacycline in 108 su…
Phase 4 • Sponsor: Clinical Hospital Centre Zagreb • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Could early antibiotic stop be safe for high-risk blood cancer patients?
Disease control Recruiting nowThis study looks at whether it is safe to stop antibiotics early in adults with high-risk blood cancers or those who have had stem cell transplants or CAR T-cell therapy. Participants will be randomly assigned to stop antibiotics once their fever goes away or continue until their…
Sponsor: Peter MacCallum Cancer Centre, Australia • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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New trial aims to stop infections in blood cancer patients
Disease control Recruiting nowThis study compares different ways to prevent infections in people with blood cancers like myeloma, leukemia, and lymphoma. About 900 participants will receive either daily antibiotics or immunoglobulin therapy, or a combination. The goal is to see which approach works best to ke…
Phase 2/3 • Sponsor: Monash University • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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New antibiotic JKN2501 enters first human tests
Disease control Recruiting nowThis early-phase trial tests the safety and tolerability of a new antibiotic called JKN2501 in 66 healthy adults in China. Participants receive either the drug or a placebo by IV infusion, and researchers monitor for side effects and how the drug moves through the body. The goal …
Phase 1 • Sponsor: Joincare Pharmaceutical Group Industry Co., Ltd • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New scan could light up hidden infections
Diagnosis Recruiting nowThis early study is testing a radioactive tracer called [18F]F-TMP that is injected into the body and then tracked with a PET/CT scan. The goal is to see if the tracer collects at sites of bacterial infection, making them visible on the scan. Twenty adults with known or suspected…
Phase 1 • Sponsor: University of Pennsylvania • Aim: Diagnosis
Last updated Sep 10, 2026 00:00 UTC
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Fast new swab test could speed up vaginitis diagnosis
Diagnosis Recruiting nowThis study will test a new diagnostic device called the Nanopath assay, which aims to quickly detect bacteria or yeast causing vaginitis. Up to 1000 women with symptoms like itching or discharge will provide vaginal swab samples, either collected by a clinician or themselves. The…
Sponsor: Nanopath, Inc • Aim: Diagnosis
Last updated Jul 22, 2026 00:00 UTC
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Simple blood test could save babies from unnecessary antibiotics
Diagnosis Recruiting nowThis pilot study tests a new blood test that looks at markers on white blood cells to tell if a feverish baby under 3 months has a serious bacterial infection. Researchers will collect an extra small blood sample from 180 infants in the emergency department. The goal is to see if…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Diagnosis
Last updated Jun 27, 2026 12:23 UTC
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New blood test aims to detect hidden infections in vulnerable patients
Diagnosis Recruiting nowThis study is testing whether a blood test called Karius Spectrum can help doctors find infections faster in adults with weakened immune systems (e.g., organ transplant recipients, cancer patients). The test looks for DNA from bacteria, fungi, viruses, and parasites in the blood.…
Sponsor: Karius, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 09:00 UTC
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New test aims to stop unnecessary antibiotics for respiratory infections
Diagnosis Recruiting nowThis study is testing a new diagnostic tool that helps doctors quickly tell if a respiratory infection is caused by bacteria or a virus. The goal is to see if using this test leads to better treatment decisions, fewer unnecessary antibiotics, and lower healthcare costs. About 100…
Sponsor: The University of Texas Health Science Center, Houston • Aim: Diagnosis
Last updated Jun 27, 2026 08:13 UTC
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Kangaroo care could slash sepsis risk in tiny newborns
Prevention Recruiting nowThis study tests whether increasing kangaroo care (skin-to-skin contact) in neonatal intensive care units can reduce severe infections and antibiotic-resistant bacteria in very premature infants (born before 32 weeks). Over 3,000 babies across multiple hospitals will be involved.…
Sponsor: PENTA Foundation • Aim: Prevention
Last updated Jun 27, 2026 12:00 UTC
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Cat bite antibiotics: could less be more?
Prevention Recruiting nowThis study looks at whether taking antibiotics for just one day after a cat bite to the hand or forearm works as well as the usual five-day course, or even a placebo. About 72 adults who are bitten and seek care within 24 hours will be randomly assigned to one of three groups. Th…
Phase 4 • Sponsor: University of Missouri-Columbia • Aim: Prevention
Last updated Jun 27, 2026 07:54 UTC
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New pump lets kids get antibiotics at home, not hospital
Symptom relief Recruiting nowThis study tests whether giving antibiotics through a small, portable pump over 24 hours is safe and cost-effective for children with serious bacterial infections. About 150 kids who are stable enough for home care will receive the pump instead of multiple daily hospital injectio…
Phase 3 • Sponsor: Tampere University Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 12:30 UTC
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Can viruses that eat bacteria beat lung infections? new study seeks answers
Knowledge-focused Recruiting nowThis study is recruiting 100 adults with hard-to-treat nontuberculous mycobacterial (NTM) lung infections to see if phage therapy—using viruses that kill bacteria—can help. Researchers will collect blood and airway samples to find biological markers that show whether the treatmen…
Sponsor: NYU Langone Health • Aim: Knowledge-focused
Last updated Sep 03, 2026 00:00 UTC
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Color-Coded triage: a quick way to spot sick kids?
Knowledge-focused Recruiting nowThis study looks at whether the color-coded triage system (Red, Yellow, Green) used in Turkish emergency departments can accurately predict which children with fever will become seriously ill. Researchers will track 3,000 children aged 0-18 who come to the emergency room with a f…
Sponsor: TC Erciyes University • Aim: Knowledge-focused
Last updated Aug 07, 2026 00:00 UTC
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New rapid test could speed up sepsis diagnosis in ER
Knowledge-focused Recruiting nowThis study is testing a new rapid diagnostic device called In-Dx to quickly identify infections and antibiotic resistance in emergency patients with suspected sepsis. Researchers will compare the device's results to standard lab cultures using stored samples from 2,500 patients. …
Sponsor: Michigan State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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CF breakthrough may lower antibiotic doses, reduce side effects
Knowledge-focused Recruiting nowThis study looks at how the cystic fibrosis drug ETI affects the way the body handles antibiotics. Researchers want to see if people on ETI need lower antibiotic doses to treat lung infections, which could reduce harmful side effects like hearing loss or kidney damage. The study …
Sponsor: Fondation Ildys • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:03 UTC
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Could personalized antibiotic dosing save lives in liver cirrhosis?
Knowledge-focused Recruiting nowThis study is observing 1,000 people with liver cirrhosis who have bacterial infections and are being treated with β-lactam antibiotics. Researchers want to see how the body processes these drugs and whether personalized dosing could improve survival. The study is observational, …
Sponsor: The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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Scientists launch major study to unlock secrets of respiratory infections
Knowledge-focused Recruiting nowThis study aims to collect blood and saliva samples from 2000 adults who come to the emergency room with a suspected respiratory infection. Researchers will use these samples to better understand how the body responds to infections and to find new ways to diagnose and treat them.…
Sponsor: The University of Hong Kong • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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New registry aims to improve meningitis treatment for kids
Knowledge-focused Recruiting nowThis study is creating a registry of 600 children under 18 with meningitis treated at hospitals across Brazil. Researchers will collect data during and after hospitalization to see how well current treatments work and what long-term problems, like hearing loss, occur. The goal is…
Sponsor: Hospital Israelita Albert Einstein • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:29 UTC
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Heart infection survivors test rehab to boost recovery
Knowledge-focused Recruiting nowThis study looks at how people recover after infective endocarditis, a serious heart infection. Researchers want to see if a 12-week exercise program can improve physical fitness, fatigue, and quality of life. About 50 adults who had the infection will take surveys, do interviews…
Sponsor: Region Halland • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Scientists hunt for genetic clues to severe infections in kids
Knowledge-focused Recruiting nowThis study aims to understand why some children develop severe bacterial infections that require intensive care. Researchers will analyze blood samples and medical histories from 1,401 children who were hospitalized for such infections between 2015 and 2018 in France. By comparin…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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New guidelines aim to cut unnecessary antibiotics in febrile babies
Knowledge-focused Recruiting nowThis study looks at whether a new, simpler guideline can safely reduce the number of tests, antibiotics, and hospital stays for infants under 2 months old with a fever. Researchers will compare hospitals using the new guideline to those using standard care. The goal is to find ou…
Sponsor: Region Skane • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:03 UTC
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Teens needed for First-Ever antibiotic safety study
Knowledge-focused Recruiting nowThis early-stage study is testing whether a single dose of an experimental antibiotic combination (sulopenem etzadroxil plus probenecid) is safe and tolerable in 12 adolescents already receiving standard antibiotics for a bacterial infection. Researchers will measure how the drug…
Phase 1 • Sponsor: Iterum Therapeutics, International Limited • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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New study aims to spot warning signs of deadly infections in kids
Knowledge-focused Recruiting nowThis study will follow 3,000 children hospitalized with severe bacterial infections to understand what makes them so dangerous. Researchers will collect data on the bacteria, the children's health, and the care they receive. The goal is to find risk factors and early warning sign…
Sponsor: Association Clinique Thérapeutique Infantile du val de Marne • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC
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New study aims to cut unnecessary antibiotics in ICU patients
Knowledge-focused Recruiting nowThis study tests whether using changes in procalcitonin levels over time (kinetics) is better than a single measurement for deciding when to start antibiotics in critically ill patients with suspected infection. About 250 adults in the ICU will be randomly assigned to one of two …
Sponsor: Semmelweis University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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New antibiotic combo tested in kidney patients
Knowledge-focused Recruiting nowThis early-stage study is testing a single dose of an experimental antibiotic combination (cefiderocol/xeruborbactam) given through a vein. The goal is to see how safe it is and how the body processes it in 40 adults with different levels of kidney function, including those on di…
Phase 1 • Sponsor: Qpex Biopharma, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC
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New study aims to spot sepsis faster in ERs
Knowledge-focused Recruiting nowThis study is looking for new ways to diagnose sepsis, a life-threatening reaction to infection, earlier in the emergency room. Researchers will study the immune responses of 3,300 adults with suspected infections to find patterns that signal sepsis. The goal is to improve diagno…
Sponsor: Amsterdam University Medical Centers (UMC), Location Academic Medical Center (AMC) • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC