Methicillin-resistant staphylococcus aureus infectious disease
MONDO:0100073Infections caused by a strain of Staphylococcus aureus that is non-susceptible to the action of the antibiotic, methicillin. The mechanism of resistance usually involves modification of normal or the presence of acquired penicillin binding proteins.
Also known as: MRSA
17 clinical trials for this condition and its sub-types.
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Which antibiotic wins against MRSA in the blood? new trial aims to find out
Disease control Recruiting nowThis study compares two common antibiotics, daptomycin and vancomycin, to see which one works better for adults with MRSA bloodstream infections. About 300 participants will be randomly assigned to one of the two drugs. The goal is to find which treatment leads to fewer complicat…
Phase: PHASE4 • Sponsor: Todd C. Lee MD MPH FIDSA • Aim: Disease control
Last updated Aug 02, 2026 00:00 UTC
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Can a common antibiotic beat MRSA in kids? a trial puts TMP-SMX to the test
Disease control Recruiting nowThis trial compares two oral antibiotics—trimethoprim-sulfamethoxazole (TMP-SMX) and clindamycin—to see which works better for children with invasive MRSA infections, such as bone, joint, or deep tissue infections. About 100 children aged 60 days to 18 years will take one of the …
Phase: PHASE4 • Sponsor: Indiana University • Aim: Disease control
Last updated Jul 31, 2026 00:00 UTC
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Can a simpler dosing method for MRSA work just as well?
Disease control Recruiting nowThis study tests whether a simpler way of dosing the antibiotic vancomycin (targeting a trough level of 10-15 mg/L) works as well as the more complex method (targeting AUC/MIC 400-600) for treating serious MRSA infections. About 700 adults with infections like bloodstream, lung, …
Phase: NA • Sponsor: Anthony Bai • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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New study aims to perfect dosing of common staph infection drug
Knowledge-focused Recruiting nowThis study measures the amount of free cloxacillin in the blood of adults receiving the drug as a continuous infusion for severe staph infections. Researchers want to ensure levels are not too high or too low. They will use this data to create a model that predicts the right dose…
Phase: PHASE4 • Sponsor: Emeli Månsson • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC