Methicillin-resistant staphylococcus aureus infectious disease

This trial examines whether using a quick nasal swab to check for MRSA bacteria can help doctors decide how long to treat pneumonia patients with the antibiotic vancomycin. The study compares the duration of therapy and costs before and after implementing this screening test. Par…

This study tested whether cleaning therapy dogs with a special disinfectant (chlorhexidine) before hospital visits could reduce the spread of harmful germs to children. The trial involved 45 children aged 3 to 17 who interacted with therapy dogs. Researchers checked if the cleani…

This study tested a checklist to prevent MRSA surgical site infections in over 23,000 veterans undergoing joint replacement or heart surgery. The checklist included using antibiotic ointment and antiseptic baths before surgery, plus antibiotics during surgery. Researchers measure…

This study tested whether an early, computer-guided dosing strategy for vancomycin helps children with MRSA infections reach the right drug levels faster than the usual approach. 100 children aged 1 month to 16 years took part. The goal was to improve treatment effectiveness whil…

This study tested a rapid blood test (T2Bacteria Panel) that identifies bacteria directly from blood, compared to standard blood cultures that take 1-3 days. Researchers wanted to see if using this test could help doctors stop unnecessary vancomycin (a strong antibiotic) sooner i…

This study compared two common antibiotics, doxycycline and TMP-SMX, for treating uncomplicated skin infections like boils and cellulitis. 269 people aged 9 to 85 took one of the drugs for 7 days. Researchers checked if the infection cleared up early, at the end of treatment, and…

This study tested whether a 5-day decolonization routine using nasal ointment, mouth rinse, and body wash could prevent MRSA infections in over 2,000 adults carrying the bacteria after hospital discharge. Participants were randomly assigned to either the decolonization regimen or…

This study tested whether adding an oral antibiotic called clindamycin to the usual topical treatment (nasal ointment and special baths) helps clear MRSA bacteria from the throat. Fifty-three adults who still carried MRSA in their throat after standard treatment took either clind…

This study tested whether combining personal hygiene (using medicated washes and ointments) with household cleaning can prevent MRSA skin infections. Over 800 people from households with a recent MRSA infection took part. The goal was to see if this combined approach reduces the …

This completed study tracked 581 hospitalized children aged 1-16 to see how antibiotic treatment affects the development of MRSA in the nose. Researchers compared children who received antibiotics to those who did not. The goal is to understand how antibiotic use drives antimicro…