Simpler antibiotic dosing may be just as effective for MRSA

NCT ID NCT04793152

First seen Jan 24, 2026 · Last updated May 14, 2026 · Updated 13 times

Summary

This study tests whether a simpler method of dosing the antibiotic vancomycin works as well as the current standard for treating serious MRSA infections. The simpler method targets a specific blood level (trough level), while the standard method uses a more complex calculation (AUC/MIC). About 700 adults with serious MRSA infections will be randomly assigned to one of the two dosing strategies. The main goal is to see if the simpler method is not worse at preventing treatment failure, including death or persistent infection, within 90 days.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hamilton Health Sciences

    RECRUITING

    Hamilton, Ontario, L8L 2X2, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Kingston Health Sciences Centre

    RECRUITING

    Kingston, Ontario, K7L 2V7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • McGill University Health Centre

    RECRUITING

    Montreal, Quebec, H3H 2R9, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • St. Joseph's Healthcare Hamilton

    RECRUITING

    Hamilton, Ontario, L8N 4A6, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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