Can a simpler dosing method for MRSA work just as well?
NCT ID NCT04793152
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a simpler way of dosing the antibiotic vancomycin (targeting a trough level of 10-15 mg/L) works as well as the more complex method (targeting AUC/MIC 400-600) for treating serious MRSA infections. About 700 adults with infections like bloodstream, lung, or bone infections will be randomly assigned to one of the two dosing strategies. The main goal is to see if the simpler method is not worse at preventing death or treatment failure within 90 days.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Hamilton Health Sciences
RECRUITINGHamilton, Ontario, L8L 2X2, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Kingston Health Sciences Centre
RECRUITINGKingston, Ontario, K7L 2V7, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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McGill University Health Centre
RECRUITINGMontreal, Quebec, H3H 2R9, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Joseph's Healthcare Hamilton
RECRUITINGHamilton, Ontario, L8N 4A6, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••