Can a simpler dosing method for MRSA work just as well?
NCT ID NCT04793152
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether a simpler way of dosing the antibiotic vancomycin (targeting a trough level of 10-15 mg/L) works as well as the more complex method (targeting AUC/MIC 400-600) for treating serious MRSA infections. About 700 adults with infections like bloodstream, lung, or bone infections will be randomly assigned to one of the two dosing strategies. The main goal is to see if the simpler method is not worse at preventing death or treatment failure within 90 days.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hamilton Health Sciences
RECRUITINGHamilton, Ontario, L8L 2X2, Canada
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Kingston Health Sciences Centre
RECRUITINGKingston, Ontario, K7L 2V7, Canada
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McGill University Health Centre
RECRUITINGMontreal, Quebec, H3H 2R9, Canada
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St. Joseph's Healthcare Hamilton
RECRUITINGHamilton, Ontario, L8N 4A6, Canada
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