New hope for Kids' diarrhea: drug plus fluids tested

NCT ID NCT07285785

Recruiting now Disease control Sponsor: Bausch Health Americas, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 2 times

Summary

This study tests how the drug rifaximin (Xifaxan) works in children aged 6 to 11 with acute diarrhea likely caused by bacteria. Half the children get the drug plus oral rehydration therapy, the other half get rehydration alone. Researchers want to see if adding the drug helps diarrhea resolve faster and is safe for kids.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: rifaximin (Xifaxan) 200 mg tablet
What this could lead to: If it works, this could provide a new treatment option for bacterial diarrhea in children, shortening illness and reducing symptoms.
What could go wrong: This is a small Phase 4 study with only 54 children, so results may not apply broadly. Rifaximin may not speed recovery over rehydration alone, and side effects are possible.

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Conditions

The condition(s) this trial relates to.

acute diarrhea bacterial infectious disease diarrheal disease gastroenteritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE DIARRHEA BACTERIAL INFECTION DIARRHEA GASTROENTERITIS

Contacts and locations

Locations

Alliance Research Institute
RECRUITING

Lynwood, California, 90262, United States
Cyn3rgy Research Corporation
RECRUITING

Gresham, Oregon, 97030, United States
Direct Helpers
RECRUITING

Hialeah, Florida, 33012, United States
Innovative Clinical Research Center
RECRUITING

Island Lake, Illinois, 60042, United States
LinQ Research
RECRUITING

Rosharon, Texas, 77583, United States
Little Stars Pediatrics / Tattva Trials
RECRUITING

Prosper, Texas, 75078, United States
Oceane7 Medical & Research Center, Inc
RECRUITING

Miami, Florida, 33144, United States
Rophe Adult & Pediatric Medicine
RECRUITING

Union City, Georgia, 30291, United States
SouthCoast Research Center
RECRUITING

Miami, Florida, 33136, United States
Tekton Research
RECRUITING

Richmond, Virginia, 23233, United States

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