New trial aims to stop infections in blood cancer patients

NCT ID NCT07202091

Recruiting now Disease control Sponsor: Monash University Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares different ways to prevent infections in people with blood cancers like myeloma, leukemia, and lymphoma. About 900 participants will receive either daily antibiotics or immunoglobulin therapy, or a combination. The goal is to see which approach works best to keep patients infection-free and reduce the need for emergency care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Trimethoprim-sulfamethoxazole (co-trimoxazole) or doxycycline, plus amoxicillin/clavulanic acid and ciprofloxacin
What this could lead to: If successful, this could identify the best way to prevent serious infections in people with blood cancers, reducing hospital visits and improving quality of life.
What could go wrong: This is an early-to-mid-stage trial, so results may not apply to all patients. Antibiotics can cause side effects like allergic reactions or resistance, and immunoglobulin may not be better than stopping it.

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Conditions

The condition(s) this trial relates to.

Infections leukemia lymphoma neoplasm non-Hodgkin lymphoma plasma cell myeloma plasma cell neoplasm bacterial infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LEUKEMIA MYELOMA NON-HODGKIN'S LYMPHOMA

Contacts and locations

Locations

Austin Hospital
RECRUITING

Melbourne, Victoria, 3004, Australia
Northern Health
RECRUITING

Melbourne, Victoria, 3004, Australia
Royal Adelaide Hospital
RECRUITING

Adelaide, South Australia, 5000, Australia

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