Monash University

This study compares giving antibiotics only during heart surgery versus continuing them for 24 or 48 hours after. The goal is to see if shorter use prevents surgical site infections just as well, while reducing side effects and costs. About 9,180 adults having heart surgery throu…

This study looks at different ways to prevent serious infections in people with blood cancers like myeloma, leukemia, and lymphoma. About 900 participants who have been on immunoglobulin therapy for at least 6 months will either stop it, switch to antibiotics, or continue current…

This study tests different ways to prevent serious infections in people with blood cancers like myeloma, lymphoma, and leukemia. About 900 participants will receive either antibiotics or immunoglobulin therapy to see which approach works best. The goal is to reduce severe infecti…

This study is testing whether giving patients more oxygen (80%) during major surgery reduces wound infections compared to lower oxygen levels (30% or 50%). It will enroll 7,800 adults having planned surgeries lasting at least 2 hours. The goal is to see if extra oxygen helps peop…

This study tests different ways to prevent serious infections in people with blood cancers like myeloma, lymphoma, and leukemia. About 900 participants will receive either antibiotics or immunoglobulin to see which approach works best. The goal is to reduce severe infections and …

This study compares two common treatments—immunoglobulin and antibiotics—to see which is better at preventing serious infections in people with blood cancers like myeloma, lymphoma, or leukemia. About 900 adults will take part. The goal is to find the safest and most effective wa…

This large study tests whether giving lidocaine (a common numbing medicine) through an IV during breast cancer surgery can prevent moderate to severe pain that lasts for a year or more. About 4,300 women having mastectomy or lumpectomy will be randomly assigned to receive lidocai…

This study looks at how syphilis bacteria spread in women and men who have sex with women only, even when there are no visible sores. Researchers will collect swabs and blood samples from 480 participants to see if the bacteria are alive and can be passed to others. The goal is t…