Monash University
Clinical trials sponsored by Monash University, explained in plain language.
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New gene-silencing drug aims to lower bad cholesterol without permanent DNA changes
Disease control Not yet recruitingThis early-stage study tests STX-1150, a new medicine that temporarily turns off a gene (PCSK9) in the liver to lower bad cholesterol (LDL-C). It does not change your DNA. Up to 64 adults with high LDL-C will receive one or more doses and be followed for a year. The main goal is …
Phase: PHASE1 • Sponsor: Monash University • Aim: Disease control
Last updated Jun 27, 2026 09:08 UTC
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Heart surgery monitor under scrutiny: is it necessary?
Knowledge-focused Not yet recruitingThis study looks at whether using a special heart monitor (pulmonary artery catheter) during open heart surgery is necessary. About 1600 adults having heart surgery will be randomly assigned to either get the monitor or not. Researchers will compare how well they recover, focusin…
Phase: NA • Sponsor: Monash University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Weight stigma in pregnancy: a hidden risk?
Knowledge-focused Not yet recruitingThis study will follow 800 pregnant women to see if weight stigma and discrimination contribute to complications like gestational diabetes. Researchers will also examine psychological factors such as trauma and eating disorders. The goal is to better understand the link between b…
Sponsor: Monash University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC