Could early antibiotic stop be safe for high-risk blood cancer patients?

NCT ID NCT07051525

Recruiting now Disease control Sponsor: Peter MacCallum Cancer Centre, Australia Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether it is safe to stop antibiotics early in adults with high-risk blood cancers or those who have had stem cell transplants or CAR T-cell therapy. Participants will be randomly assigned to stop antibiotics once their fever goes away or continue until their white blood cell count recovers. The goal is to reduce antibiotic use and side effects while keeping patients safe in the hospital.

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Conditions

The condition(s) this trial relates to.

acute leukemia bacterial infectious disease Febrile Neutropenia leukemia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CART THERAPY INFECTIONS, BACTERIAL LEUKEMIA TRANSPLANTATION, STEM CELL

Contacts and locations

Locations

Peter MacCallum Cancer Centre
RECRUITING

Melbourne, Victoria, 3000, Australia
Royal Melbourne Hospital
RECRUITING

Melbourne, Victoria, 3050, Australia

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