Leprosy

This study tests an experimental drug called dovramilast in 45 adults with moderate to severe leprosy type 2 reaction, a painful skin condition. Participants receive either dovramilast (100 mg or 150 mg) or standard treatments like prednisolone or thalidomide. The goal is to see …

This study is testing whether a new approach—using ultrasound to guide a tiny needle to collect fluid near the ulnar nerve, then analyzing it for leprosy bacteria DNA—can more accurately diagnose leprosy and confirm when it's cured. Researchers will follow 108 participants for on…

This phase 3 trial tests whether a combination of two antibiotics (bedaquiline and rifampicin) can better prevent leprosy than the current standard single dose of rifampicin. Over 124,000 people living near a leprosy patient in the Comoros will receive either the new two-dose reg…

This study in Bangladesh tests whether giving a single dose of the antibiotic rifampin to people who live with or near leprosy patients can prevent infection. Researchers will use a new fingerprick blood test to measure infection markers before and after treatment. The goal is to…

This study is collecting skin and blood samples from 830 people with chronic inflammatory skin diseases like psoriasis, eczema, and lupus. Researchers want to find biological markers that can predict how well a person will respond to treatment after one year. The goal is to move …