New ultrasound and DNA test could revolutionize leprosy diagnosis
NCT ID NCT07515989
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is testing whether a new approach—using ultrasound to guide a tiny needle to collect fluid near the ulnar nerve, then analyzing it for leprosy bacteria DNA—can more accurately diagnose leprosy and confirm when it's cured. Researchers will follow 108 participants for one year, comparing this method to standard tests. If it works, it could lead to earlier treatment and fewer long-term disabilities.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Ultrasound-guided perineural subcutaneous aspirate with PCR analysis
- What this could lead to
- If successful, this could provide a more accurate way to diagnose leprosy early and confirm when the disease is cured, potentially reducing nerve damage and disability.
- What could go wrong
- This is a small, early-stage study (108 participants) testing a new diagnostic method. The technique may not prove more accurate than existing tests, and results may not apply to all leprosy patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
University Hospital of Brasília
RECRUITINGBrasília, Federal District, 70.830-200, Brazil
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