POLYNEUROPATHIES
Clinical trials for POLYNEUROPATHIES explained in plain language.
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Gene-Editing shot aims to halt rare nerve disease in phase 3 trial
Disease control Recruiting nowThis study tests a single dose of NTLA-2001, a gene-editing therapy, in 60 adults with hereditary transthyretin amyloidosis with polyneuropathy (ATTRv-PN), a genetic disease that damages nerves. The goal is to see if the treatment can stop or slow the disease by lowering a harmfu…
Matched conditions: POLYNEUROPATHIES
Phase: PHASE3 • Sponsor: Intellia Therapeutics • Aim: Disease control
Last updated May 06, 2026 16:02 UTC
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New Ultrasound-Guided test could revolutionize leprosy diagnosis
Diagnosis Recruiting nowThis study is testing whether a new method—using ultrasound to guide a small needle sample from near the nerve—can find leprosy bacteria more accurately than current tests. About 108 people with suspected leprosy will be followed for one year to see if this approach helps diagnos…
Matched conditions: POLYNEUROPATHIES
Phase: NA • Sponsor: University of Brasilia • Aim: Diagnosis
Last updated May 14, 2026 12:06 UTC
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Breakthrough trial hopes to stop rare genetic disease in its tracks
Prevention Recruiting nowThis study tests an experimental drug called acoramidis in 587 adults who carry a gene mutation for transthyretin amyloidosis (ATTR) but have no symptoms yet. The drug aims to stabilize a protein in the blood to prevent it from forming harmful plaques in the heart and nerves. If …
Matched conditions: POLYNEUROPATHIES
Phase: PHASE3 • Sponsor: Eidos Therapeutics, a BridgeBio company • Aim: Prevention
Last updated May 17, 2026 01:17 UTC
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Blood thinner patients get ultrasound after muscle test to spot hidden bleeding
Knowledge-focused Recruiting nowThis study checks whether a common nerve test called needle EMG is safe for people taking blood thinners (DOACs). About 30 minutes after the test, researchers use ultrasound to look for small muscle bleeds (hematomas) where the needle went in. The goal is to see if the risk of bl…
Matched conditions: POLYNEUROPATHIES
Sponsor: Masaryk University • Aim: Knowledge-focused
Last updated May 15, 2026 11:54 UTC